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  • Jin-Xiong She
2020

A 73-gene proliferative transcriptomic signature predicts uterine serous carcinoma patient survival and response to primary therapy

Tran, L. K. H., Tran, P. M. H., Mysona, D. P., Purohit, S. B., Myers, E., Lee, W. S., Dun, B., Xu, D., Liu, H., Hopkins, D., Nechtman, J., Scelsi, C. L., Mittal, P. K., Kleven, D., Wallbillich, J. J., Rungruang, B., Ghamande, S. & She, J. X., Jan 1 2020, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Better survival is observed in cervical cancer patients positive for specific anti-glycan antibodies and receiving brachytherapy

Purohit, S., Ferris, D. G., Alvarez, M., Tran, P. M. H., Tran, L. K. H., Mysona, D. P., Hopkins, D., Zhi, W., Dun, B., Wallbillich, J. J., Cummings, R. D., Wang, P. G. & She, J. X., Jan 1 2020, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers

Mysona, D. P., Tran, L. K. H., Tran, P. M. H., Gehrig, P. A., Van Le, L., Ghamande, S., Rungruang, B. J., Java, J., Mann, A. K., Liao, J., Kapp, D. S., Santos, B. D., She, J. X. & Chan, J. K., Jan 2020, In : Gynecologic Oncology. 156, 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

2019

A combined score of clinical factors and serum proteins can predict time to recurrence in high grade serous ovarian cancer

Mysona, D., Pyrzak, A., Purohit, S., Zhi, W., Sharma, A., Tran, L., Tran, P., Bai, S., Rungruang, B., Ghamande, S. & She, J. X., Mar 2019, In : Gynecologic Oncology. 152, 3, p. 574-580 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential

Gobin, E., Bagwell, K., Wagner, J., Mysona, D., Sandirasegarane, S., Smith, N., Bai, S., Sharma, A., Schleifer, R. & She, J. X., Jun 14 2019, In : BMC Cancer. 19, 1, 581.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Association of gluten intake during the first 5 years of life with incidence of celiac disease autoimmunity and celiac disease among children at increased risk

Andrén Aronsson, C., Lee, H. S., Hård Af Segerstad, E. M., Uusitalo, U., Yang, J., Koletzko, S., Liu, E., Kurppa, K., Bingley, P. J., Toppari, J., Ziegler, A. G., She, J. X., Hagopian, W. A., Rewers, M., Akolkar, B., Krischer, J. P., Virtanen, S. M., Norris, J. M. & Agardh, D., Aug 13 2019, In : JAMA - Journal of the American Medical Association. 322, 6, p. 514-523 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Cell-based high throughput screening identified a novel compound that promotes regulatory T cells and prevents autoimmune colitis

Mao, R., Liu, H., Yi, B., Purohit, S., Kuczma, M., Kraj, P. & She, J. X., Nov 2019, In : Biochemical Pharmacology. 169, 113618.

Research output: Contribution to journalArticle

Early probiotic supplementation and the risk of celiac disease in children at genetic risk

TEDDY study group, Aug 2019, In : Nutrients. 11, 8, 1790.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families

The TEDDY study group, Apr 1 2019, In : Diabetes. 68, 4, p. 847-857 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Identification of novel T1D risk loci and their association with age and islet function at diagnosis in autoantibody-positive T1D individuals: Based on a two-stage genome-wide association study

Zhu, M., Xu, K., Chen, Y., Gu, Y., Zhang, M., Luo, F., Liu, Y., Gu, W., Hu, J., Xu, H., Xie, Z., Sun, C., Li, Y., Sun, M., Xu, X., Hsu, H. T., Chen, H., Fu, Q., Shi, Y., Xu, J. & 33 others, Ji, L., Liu, J., Bian, L., Zhu, J., Chen, S., Xiao, L., Li, X., Jiang, H., Shen, M., Huang, Q., Fang, C., Li, X., Huang, G., Fan, J., Jiang, Z., Jiang, Y., Dai, J., Ma, H., Zheng, S., Cai, Y., Dai, H., Zheng, X., Zhou, H., Ni, S., Jin, G., She, J. X., Yu, L., Polychronakos, C., Hu, Z., Zhou, Z., Weng, J., Shen, H. & Yang, T., Aug 1 2019, In : Diabetes Care. 42, 8, p. 1414-1421 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study

The TEDDY study group, Feb 1 2019, In : Pediatric Diabetes. 20, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolite-related dietary patterns and the development of islet autoimmunity

The TEDDY study group, Dec 1 2019, In : Scientific reports. 9, 1, 14819.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Predicting islet cell autoimmunity and type 1 diabetes: An 8-year teddy study progress report

TEDDY study group, Jun 1 2019, In : Diabetes Care. 42, 6, p. 1051-1060 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

The TEDDY study group, May 2019, In : Pediatric Diabetes. 20, 3, p. 263-270 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study

Beyerlein, A., Bonifacio, E., Vehik, K., Hippich, M., Winkler, C., Frohnert, B. I., Steck, A. K., Hagopian, W. A., Krischer, J. P., Lernmark, Å., Rewers, M. J., She, J. X., Toppari, J., Akolkar, B., Rich, S. S. & Ziegler, A. G., Sep 1 2019, In : Journal of medical genetics. 56, 9, p. 602-605 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children

TEDDY study group, Sep 18 2019, In : BMC pediatrics. 19, 1, 339.

Research output: Contribution to journalArticle

Open Access

Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children

for the TEDDY Study Group*, Jan 1 2019, In : Diabetes. 68, 1, p. 119-130 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2018

Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study

for the TEDDY Study Group, Mar 1 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
1 Scopus citations

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journalArticle

2 Scopus citations

Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

Tailor, P. D., Kodeboyina, S. K., Bai, S., Sharma, S., Ratnani, A., Copland, J. A., She, J-X., Sharma, A. K. & Patel, N., Apr 1 2018, In : Oncotarget. 9, 25, p. 17876-17888 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Early infant diet and islet autoimmunity in the TEDDY study

Uusitalo, U., Lee, H. S., Aronsson, C. A., Vehik, K., Yang, J., Hummel, S., Silvis, K., Lernmark, Å., Rewers, M., Hagopian, W., She, J. X., Simell, O., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J., Virtanen, S. M. & Norris, J. M., Mar 1 2018, In : Diabetes Care. 41, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children

for the TEDDY Study Group, Apr 2018, In : PLoS Medicine. 15, 4, e1002548.

Research output: Contribution to journalArticle

24 Scopus citations

Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - A preliminary report

Shiao, S. P. K., Xiao, H., Dong, L., Wang, X., Liu, K., She, J. & Shi, H., May 22 2018, In : Oncotarget. 9, 39, p. 25557-25571 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies

on behalf of & TEDDY study group, Jan 2018, In : Journal of Autoimmunity. 86, p. 93-103 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort

TEDDY study group, May 2018, In : Journal of Autoimmunity. 89, p. 90-100 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J. X., Belin de Chantemele, E. J. & Csányi, G., Sep 2018, In : British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

KLHL5 knockdown increases cellular sensitivity to anticancer drugs

Schleifer, R. J., Li, S., Nechtman, W., Miller, E., Bai, S., Sharma, A. K. & She, J-X., Dec 1 2018, In : Oncotarget. 9, 100, p. 37429-37438 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Purohit, S. B., Li, T., Guan, W., Song, X., Song, J., Tian, Y., Li, L., Sharma, A. K., Dun, B., Mysona, D., Ghamande, S. A., Rungruang, B. J., Cummings, R. D., Wang, P. G. & She, J-X., Dec 1 2018, In : Nature communications. 9, 1, 258.

Research output: Contribution to journalArticle

18 Scopus citations

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

for the TEDDY Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Lernmark, Å., Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J-X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., Jan 1 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Proteins of TNF-α and IL6 pathways are elevated in serum of type-1 diabetes patients with microalbuminuria

Purohit, S. B., Sharma, A. K., Zhi, W., Bai, S., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D. & She, J-X., Jan 31 2018, In : Frontiers in immunology. 9, JAN, 154.

Research output: Contribution to journalArticle

1 Scopus citations

Proteomic approach to identify biomarkers for invasive cervix cancer - a prospective pilot study

Mysona, D., Pyrzak, A., Allen, J., Powell, M., Kleven, D., Zhi, W., Sharma, A., Bai, S., She, J. X., Rungruang, B. & Ghamande, S., Jan 1 2018, In : European Journal of Gynaecological Oncology. 39, 5, p. 737-742 6 p.

Research output: Contribution to journalArticle

Temporal development of the gut microbiome in early childhood from the TEDDY study

Stewart, C. J., Ajami, N. J., O’Brien, J. L., Hutchinson, D. S., Smith, D. P., Wong, M. C., Ross, M. C., Lloyd, R. E., Doddapaneni, H. V., Metcalf, G. A., Muzny, D., Gibbs, R. A., Vatanen, T., Huttenhower, C., Xavier, R. J., Rewers, M., Hagopian, W., Toppari, J., Ziegler, A. G., She, J-X. & 6 others, Akolkar, B., Lernmark, A., Hyoty, H., Vehik, K., Krischer, J. P. & Petrosino, J. F., Oct 25 2018, In : Nature. 562, 7728, p. 583-588 6 p.

Research output: Contribution to journalLetter

107 Scopus citations

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

The TEDDY study group, Dec 1 2018, In : Current diabetes reports. 18, 12, 136.

Research output: Contribution to journalReview article

8 Scopus citations

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

Vatanen, T., Franzosa, E. A., Schwager, R., Tripathi, S., Arthur, T. D., Vehik, K., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Stewart, C. J., Ajami, N. J., Petrosino, J. F., Gevers, D., Lähdesmäki, H., Vlamakis, H. & 2 others, Huttenhower, C. & Xavier, R. J., Oct 25 2018, In : Nature. 562, 7728, p. 589-594 6 p.

Research output: Contribution to journalLetter

78 Scopus citations
2017

Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity

for the TEDDY Study Group, May 16 2017, In : BMC pediatrics. 17, 1, 127.

Research output: Contribution to journalArticle

6 Scopus citations

Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity

Kemppainen, K. M., Vehik, K., Lynch, K. F., Larsson, H. E., Canepa, R. J., Simell, V., Koletzko, S., Liu, E., Simell, O. G., Toppari, J., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W. A., She, J-X., Akolkar, B., Schatz, D. A., Atkinson, M. A., Blaser, M. J., Krischer, J. P. & 185 others, Hyöty, H., Agardh, D., Triplett, E. W., Bautista, K., Baxter, J., Bedoy, R., Felipe-Morales, D., Driscoll, K., Frohnert, B. I., Gesualdo, P., Hoffman, M., Karban, R., Norris, J., Samper-Imaz, A., Steck, A., Waugh, K., Wright, H., Adamsson, A., Ahonen, S., Ilonen, J., Jokipuu, S., Kallio, T., Karlsson, L., Kähönen, M., Knip, M., Kovanen, L., Koreasalo, M., Kurppa, K., Latva-Aho, T., Lönnrot, M., Mäntymäki, E., Multasuo, K., Mykkänen, J., Niininen, T., Niinistö, S., Nyblom, M., Rajala, P., Rautanen, J., Riikonen, A., Riikonen, M., Rouhiainen, J., Romo, M., Simell, T., Sjöberg, M., Stenius, A., Leppänen, M., Vainionpää, S., Varjonen, E., Veijola, R., Virtanen, S. M., Vähä-Mäkilä, M., Åkerlund, M., Lindfors, K., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Adams, J., Silvis, K., Haller, M., Gardiner, M., McIndoe, R. A., Sharma, A. K., William, J., Young, G., Anderson, S. W., Jacobsen, L., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Janz, N., Kersting, M., Knopff, A., Peplow, C., Roth, R., Scholz, M., Stock, J., Warncke, K., Wendel, L., Winkler, C., Aronsson, C. A., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallström, E., Fransson, L., Gard, T., Gerardsson, J., Bennet, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonsdottir, B., Lindström, M., Lundgren, M., Månsson-Martinez, M., Markan, M., Melin, J., Mestan, Z., Ottosson, K., Rahmati, K., Ramelius, A., Salami, F., Sibthorpe, S., Sjöberg, B., Swartling, U., Amboh, E. T., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Killian, M., Crouch, C. C., Skidmore, J., Carson, J., Dalzell, M., Dunson, K., Hervey, R., Johnson, C., Lyons, R., Meyer, A., Mulenga, D., Tarr, A., Uland, M., Willis, J., Becker, D., Franciscus, M., Smith, M. E. D. E., Daftary, A., Klein, M. B., Yates, C., Abbondondolo, M., Austin-Gonzalez, S., Avendano, M., Baethke, S., Brown, R., Burkhardt, B., Butterworth, M., Clasen, J., Cuthbertson, D., Eberhard, C., Fiske, S., Garcia, D., Garmeson, J., Gowda, V., Heyman, K., Laras, F. P., Lee, H. S., Liu, S., Liu, X., Lynch, K., Malloy, J., McCarthy, C., Meulemans, S., Parikh, H., Shaffer, C., Smith, L., Smith, S., Sulman, N., Tamura, R., Uusitalo, U., Vijayakandipan, P., Wood, K., Yang, J., Ballard, L., Hadley, D., McLeod, W., Bourcier, K., Briese, T., Johnson, S. B., Yu, L., Miao, D., Bingley, P., William's, A., Chandler, K., Rokni, S., Willia, C., Wyatt, R., George, G., Grace, S. & Mulholland, N., Dec 2017, In : JAMA Pediatrics. 171, 12, p. 1217-1225 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Blood-based biomarkers for precision medicine in lung cancer: Precision radiation therapy

De Ruysscher, D., Jin, J., Lautenschlaeger, T., She, J. X., Liao, Z. & Kong, F. M. S., Dec 1 2017, In : Translational Lung Cancer Research. 6, 6, p. 661-669 9 p.

Research output: Contribution to journalReview article

4 Scopus citations

Co-occurrence of type 1 diabetes and celiac disease autoimmunity

Hagopian, W., Lee, H. S., Liu, E., Rewers, M., She, J. X., Ziegler, A. G., Lernmark, A., Toppari, J., Rich, S. S., Krischer, J. P., Erlich, H., Akolkar, B. & Agardh, D., Nov 2017, In : Pediatrics. 140, 5, e20171305.

Research output: Contribution to journalArticle

17 Scopus citations

Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life

TEDDY study group, May 2017, In : Clinical Gastroenterology and Hepatology. 15, 5, p. 694-702.e5

Research output: Contribution to journalArticle

42 Scopus citations

First infant formula type and risk of islet autoimmunity in the environmental determinants of diabetes in the young (TEDDY) study

Hummel, S., Beyerlein, A., Tamura, R., Uusitalo, U., Andŕen Aronsson, C., Yang, J., Riikonen, A., Lernmark, A., Rewers, M. J., Hagopian, W. A., She, J. X., Simell, O. G., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Virtanen, S. M. & Norris, J. M., Mar 1 2017, In : Diabetes Care. 40, 3, p. 398-404 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Genetic and environmental interactions modify the risk of diabetes-related autoimmunity by 6 years of age: The teddy study

Krischer, J. P., Lynch, K. F., Lernmark, A., Hagopian, W. A., Rewers, M. J., She, J. X., Toppari, J., Ziegler, A. G. & Akolkar, B., Sep 1 2017, In : Diabetes Care. 40, 9, p. 1194-1202 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Identification of serum proteins and multivariate models for diagnosis and therapeutic monitoring of lung cancer

Ma, R., Xu, H., Wu, J., Sharma, A. K., Bai, S., Dun, B., Jing, C., Cao, H., Wang, Z., She, J-X. & Feng, J., Jan 1 2017, In : Oncotarget. 8, 12, p. 18901-18913 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study

Ancillary Studies, Diet, Genetics, Human Subjects/Publicity/Publications, Immune Markers, Infectious Agents, Laboratory Implementation, Maternal Studies, Psychosocial, Quality Assurance, Steering, Study Coordinators, Celiac Disease, Clinical Implementation & TEDDY study group, Nov 1 2017, In : Acta Diabetologica. 54, 11, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study

Yang, J., Tamura, R. N., Aronsson, C. A., Uusitalo, U. M., Lernmark, Å., Rewers, M., Hagopian, W. A., She, J. X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Agardh, D., Feb 14 2017, In : British Journal of Nutrition. 117, 3, p. 466-472 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Psychological manifestations of celiac disease autoimmunity in young children

The TEDDY study group, Mar 2017, In : Pediatrics. 139, 3, e20162848.

Research output: Contribution to journalArticle

16 Scopus citations

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

On behalf of the TEDDY Study Group, Oct 1 2017, In : Diabetologia. 60, 10, p. 1931-1940 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history on the progression from multiple autoantibodies to type 1 diabetes: A teddy study report

Krischer, J. P., Liu, X., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J. X., Toppari, J., Ziegler, A. G. & Akolkar, B., Dec 1 2017, In : Diabetes. 66, 12, p. 3122-3129 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
2016
6 Scopus citations