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Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Robert William Caldwell
2020

Arginase Pathway in Acute Retina and Brain Injury: Therapeutic Opportunities and Unexplored Avenues

Fouda, A. Y., Eldahshan, W., Narayanan, S. P., Caldwell, R. W. & Caldwell, R. B., Mar 17 2020, In : Frontiers in Pharmacology. 11, 277.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2019

Age-dependent oxidative stress elevates arginase 1 and uncoupled nitric oxide synthesis in skeletal muscle of aged mice

Pandya, C. D., Lee, B., Toque, H. A., Mendhe, B., Bragg, R. T., Pandya, B., Atawia, R. T., Isales, C., Hamrick, M., Caldwell, R. W. & Fulzele, S., 2019, In : Oxidative medicine and cellular longevity. 2019, 1704650.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Chronic mild stress induced anxiety-like behaviors can Be attenuated by inhibition of NOX2-derived oxidative stress

Lv, H., Zhu, C., Wu, R., Ni, H., Lian, J., Xu, Y., Xia, Y., Shi, G., Li, Z., Caldwell, R. B., Caldwell, R. W., Yao, L. & Chen, Y., Jul 2019, In : Journal of Psychiatric Research. 114, p. 55-66 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
7 Scopus citations

Mechanisms of obesity-induced metabolic and vascular dysfunctions

Atawia, R. T., Bunch, K. L., Toque, H. A., Caldwell, R. B. & Caldwell, R. W., Mar 1 2019, In : Frontiers in Bioscience - Landmark. 24, 5, p. 890-934 45 p.

Research output: Contribution to journalArticle

10 Scopus citations

Regulation of MAP kinase-mediated endothelial dysfunction in hyperglycemia via arginase I and eNOS dysregulation

Mazrouei, S., Sharifpanah, F., Caldwell, R. W., Franz, M., Shatanawi, A., Muessig, J., Fritzenwanger, M., Schulze, P. C. & Jung, C., Sep 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 9, p. 1398-1411 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access
3 Scopus citations

The TNF-derived TIP peptide activates the epithelial sodium channel and ameliorates experimental nephrotoxic serum nephritis

Madaio, M. P., Czikora, I., Kvirkvelia, N., McMenamin, M., Yue, Q., Liu, T., Flores Toque, H. A., Sridhar, S., Covington, K., Alaisami, R., O'Connor, P. M., Caldwell, R. W., Chen, J., Clauss, M., Brands, M. W., Eaton, D. C., Romero Lucas, M. J. & Lucas, R., Jun 2019, In : Kidney International. 95, 6, p. 1359-1372 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Arginase: A multifaceted enzyme important in health and disease

Caldwell, R. W., Rodriguez, P. C., Toque, H. A., Priya Narayanan, S. & Caldwell, R. B., Apr 2018, In : Physiological reviews. 98, 2, p. 641-665 25 p.

Research output: Contribution to journalReview article

47 Scopus citations

Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses

Fouda, A. Y., Xu, Z., Shosha, E., Lemtalsi, T., Chen, J., Toque, H. A., Tritz, R., Cui, X., Stansfield, B. K., Huo, Y., Rodriguez, P. C., Smith, S. B., Caldwell, R. W., Narayanan, S. P. & Caldwell, R. B., Oct 1 2018, In : Cell Death and Disease. 9, 10, 1001.

Research output: Contribution to journalArticle

7 Scopus citations

Mechanisms of diabetes-induced endothelial cell senescence: Role of arginase 1

Shosha, E., Xu, Z., Priya Narayanan, S., Lemtalsi, T., Fouda, A. Y., Rojas, M., Xing, J., Fulton, D., William Caldwell, R. & Caldwell, R. B., Apr 17 2018, In : International journal of molecular sciences. 19, 4, 1215.

Research output: Contribution to journalArticle

7 Scopus citations
2017

Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock

Subramani, K., Lu, S., Warren, M., Chu, X., Flores Toque, H. A., Caldwell, R. W., Diamond, M. P. & Raju, R. P., Dec 1 2017, In : Scientific reports. 7, 1, 2671.

Research output: Contribution to journalArticle

8 Scopus citations

Netrin-1 is a novel regulator of vascular endothelial function in diabetes

Toque, H. A., Fernandez-Flores, A., Mohamed, R., Caldwell, R. B., Ramesh, G. & Caldwell, R. W., Oct 2017, In : PloS one. 12, 10, e0186734.

Research output: Contribution to journalArticle

10 Scopus citations

Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1

Bhatta, A., Yao, L., Xu, Z., Toque, H. A., Chen, J., Atawia, R. T., Fouda, A. Y., Bagi, Z., Lucas, R., Caldwell, R. B. & Caldwell, R. W., Nov 1 2017, In : Cardiovascular Research. 113, 13, p. 1664-1676 13 p.

Research output: Contribution to journalArticle

34 Scopus citations

Obesity-induced vascular inflammation involves elevated arginase activity

Yao, L., Bhatta, A., Xu, Z., Chen, J., Toque, H. A., Chen, Y., Xu, Y., Bagi, Z., Lucas, R., Huo, Y., Caldwell, R. B. & Caldwell, R. W., Nov 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 313, 5, p. R560-R571

Research output: Contribution to journalArticle

12 Scopus citations
2016

Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury

Shosha, E., Xu, Z., Yokota, H., Saul, A., Rojas, M., William Caldwell, R., Caldwell, R. B. & Priya Narayanan, S., 2016, In : Cell Death and Disease. 7, 11, e2483.

Research output: Contribution to journalArticle

19 Scopus citations

Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model

Bhatta, A., Sangani, R., Kolhe, R., Toque, H. A., Cain, M., Wong, A., Howie, N., Shinde, R., Elsalanty, M., Yao, L., Chutkan, N., Hunter, M., Caldwell, R. B., Isales, C., Caldwell, R. W. & Fulzele, S., Feb 15 2016, In : Molecular and Cellular Endocrinology. 422, p. 211-220 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy

Patel, C., Xu, Z., Shosha, E., Xing, J., Lucas, R., Caldwell, R. W., Caldwell, R. B. & Narayanan, S. P., Sep 1 2016, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 9, p. 1628-1639 12 p.

Research output: Contribution to journalArticle

5 Scopus citations