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  • Zheng Dong
2020

Canagliflozin reduces cisplatin uptake and activates Akt to protect against cisplatin-induced nephrotoxicity

Song, Z., Zhu, J., Wei, Q., Dong, G. & Dong, Z., Apr 1 2020, In : American journal of physiology. Renal physiology. 318, 4, p. F1041-F1052

Research output: Contribution to journalArticle

Irisin is induced in renal ischemia-reperfusion to protect against tubular cell injury via suppressing p53

Liu, Y., Fu, Y., Liu, Z., Shu, S., Wang, Y., Cai, J., Tang, C. & Dong, Z., Jul 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 7, 165792.

Research output: Contribution to journalArticle

miR-214 represses mitofusin-2 to promote renal tubular apoptosis in ischemic acute kidney injury

Yan, Y., Ma, Z., Zhu, J., Zeng, M., Liu, H. & Dong, Z., Apr 1 2020, In : American journal of physiology. Renal physiology. 318, 4, p. F878-F887

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis

Zhang, P., Yi, L., Qu, S., Dai, J., Li, X., Liu, B., Li, H., Ai, K., Zheng, P., Qiu, S., Li, Y., Wang, Y., Xiang, X., Chai, X., Dong, Z. & Zhang, D., Mar 6 2020, In : Molecular Therapy - Nucleic Acids. 19, p. 1027-1042 16 p.

Research output: Contribution to journalArticle

Open Access

The deacetylase sirtuin 6 protects against kidney fibrosis by epigenetically blocking β-catenin target gene expression

Cai, J., Liu, Z., Huang, X., Shu, S., Hu, X., Zheng, M., Tang, C., Liu, Y., Chen, G., Sun, L., Liu, H., Liu, F., Cheng, J. & Dong, Z., Jan 2020, In : Kidney International. 97, 1, p. 106-118 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease

Chen, G., Chen, H., Ren, S., Xia, M., Zhu, J., Liu, Y., Zhang, L., Tang, L., Sun, L., Liu, H. & Dong, Z., Aug 2019, In : Kidney International. 96, 2, p. 409-420 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Activation of BNIP3-mediated mitophagy protects against renal ischemia–reperfusion injury

Tang, C., Han, H., Liu, Z., Liu, Y., Yin, L., Cai, J., He, L., Liu, Y., Chen, G., Zhang, Z., Yin, X. M. & Dong, Z., Sep 1 2019, In : Cell Death and Disease. 10, 9, 677.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Bif-1 interacts with prohibitin-2 to regulate mitochondrial inner membrane during cell stress and apoptosis

Cho, S. G., Xiao, X., Wang, S., Gao, H., Rafikov, R., Black, S., Huang, S., Ding, H. F., Yoon, Y., Kirken, R. A., Yin, X. M., Wang, H. G. & Dong, Z., Jul 2019, In : Journal of the American Society of Nephrology. 30, 7, p. 1174-1191 18 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cell Apoptosis and Autophagy in Renal Fibrosis

Zhao, X. C., Livingston, M. J., Liang, X. L. & Dong, Z., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 557-584 28 p. (Advances in Experimental Medicine and Biology; vol. 1165).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Chronic effects of repeated low-dose cisplatin treatment in mouse kidneys and renal tubular cells

Fu, Y., Cai, J., Li, F., Liu, Z., Shu, S., Wang, Y., Liu, Y., Tang, C. & Dong, Z., Jan 1 2019, In : American Journal of Physiology - Renal Physiology. 317, 6, p. F1582-F1592

Research output: Contribution to journalArticle

Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys

Livingston, M. J., Wang, J., Zhou, J., Wu, G., Ganley, I. G., Hill, J. A., Yin, X. M. & Dong, Z., Dec 2 2019, In : Autophagy. 15, 12, p. 2142-2162 21 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Diverse Consequences in Liver Injury in Mice with Different Autophagy Functional Status Treated with Alcohol

Yan, S., Zhou, J., Chen, X., Dong, Z. & Yin, X. M., Sep 2019, In : American Journal of Pathology. 189, 9, p. 1744-1762 19 p.

Research output: Contribution to journalArticle

1 Scopus citations

EGFR drives the progression of AKI to CKD through HIPK2 overexpression

Xu, L., Li, X., Zhang, F., Wu, L., Dong, Z. & Zhang, D., Jan 1 2019, In : Theranostics. 9, 9, p. 2712-2726 15 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications

Guo, C., Dong, G., Liang, X. & Dong, Z., Apr 1 2019, In : Nature Reviews Nephrology. 15, 4, p. 220-239 20 p.

Research output: Contribution to journalReview article

11 Scopus citations

Epigenetic Regulation in Kidney Toxicity: Insights From Cisplatin Nephrotoxicity

Xiang, X., Guo, C., Tang, C., Cai, J. & Dong, Z., Mar 2019, In : Seminars in Nephrology. 39, 2, p. 152-158 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

Erratum: HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers(J Clin Invest. (2018)128:6(2419–2435) DOI: 10.1172/JCI91814)

Khambu, B., Huda, N., Chen, X., Antoine, D. J., Li, Y., Dai, G., Köhler, U. A., Zong, W. X., Waguri, S., Werner, S., Oury, T. D., Dong, Z. & Yin, X. M., May 1 2019, In : Journal of Clinical Investigation. 129, 5, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Hepatic Autophagy Deficiency Compromises Farnesoid X Receptor Functionality and Causes Cholestatic Injury

Khambu, B., Li, T., Yan, S., Yu, C., Chen, X., Goheen, M., Li, Y., Lin, J., Cummings, O. W., Lee, Y. A., Friedman, S., Dong, Z., Feng, G. S., Wu, S. & Yin, X. M., May 2019, In : Hepatology. 69, 5, p. 2196-2213 18 p.

Research output: Contribution to journalArticle

8 Scopus citations

Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation

Yang, L., Zha, Y., Ding, J., Ye, B., Liu, M., Yan, C., Dong, Z., Cui, H. & Ding, H. F., Jan 1 2019, In : Oncogenesis. 8, 1, 3.

Research output: Contribution to journalArticle

2 Scopus citations

Identification of key biomarkers in diabetic nephropathy via bioinformatic analysis

Zeng, M., Liu, J., Yang, W., Zhang, S., Liu, F., Dong, Z., Peng, Y., Sun, L. & Xiao, L., May 2019, In : Journal of cellular biochemistry. 120, 5, p. 8676-8688 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Metabolic reprogramming by MYCN confers dependence on the serine-glycine-one-carbon biosynthetic pathway

Xia, Y., Ye, B., Ding, J., Yu, Y., Alptekin, A., Thangaraju, M., Prasad, P. D., Ding, Z. C., Park, E. J., Choi, J. H., Gao, B., Fiehn, O., Yan, C., Dong, Z., Zha, Y. & Ding, H. F., Aug 1 2019, In : Cancer Research. 79, 15, p. 3837-3850 14 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Multiple-microarray analysis for identification of hub genes involved in tubulointerstial injury in diabetic nephropathy

Zeng, M., Liu, J., Yang, W., Zhang, S., Liu, F., Dong, Z., Peng, Y., Sun, L. & Xiao, L., Sep 1 2019, In : Journal of Cellular Physiology. 234, 9, p. 16447-16462 16 p.

Research output: Contribution to journalArticle

3 Scopus citations

Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation

Zheng, M., Cai, J., Liu, Z., Shu, S., Wang, Y., Tang, C. & Dong, Z., Jun 2019, In : Journal of Cellular and Molecular Medicine. 23, 6, p. 3995-4004 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Non-coding RNAs in kidney injury and repair

Liu, Z., Wang, Y., Shu, S., Cai, J., Tang, C. & Dong, Z., Aug 2019, In : American Journal of Physiology - Cell Physiology. 317, 2, p. C177-C188

Research output: Contribution to journalArticle

5 Scopus citations

p53-cyclophilin D mediates renal tubular cell apoptosis in ischemia-reperfusion-induced acute kidney injury

Yang, H., Li, R., Zhang, L., Zhang, S., Dong, W., Chen, Y., Wang, W., Li, C., Ye, Z., Zhao, X., Li, Z., Wu, Y., Zhang, M., Liu, S., Dong, Z. & Liang, X., Nov 1 2019, In : American journal of physiology. Renal physiology. 317, 5, p. F1311-F1317

Research output: Contribution to journalArticle

2 Scopus citations

P53 in kidney injury and repair: Mechanism and therapeutic potentials

Tang, C., Ma, Z., Zhu, J., Liu, Z., Liu, Y., Liu, Y., Cai, J. & Dong, Z., Mar 2019, In : Pharmacology and Therapeutics. 195, p. 5-12 8 p.

Research output: Contribution to journalReview article

11 Scopus citations

PFKFB3 in smooth muscle promotes vascular remodeling in pulmonary arterial hypertension

Kovacs, L., Cao, Y., Han, W., Meadows, L., Kovacs-Kasa, A., Kondrikov, D., Verin, A. D., Barman, S. A., Dong, Z., Huo, Y. & Su, Y., Sep 1 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

RNA interference may suppress stress granule formation by preventing argonaute 2 recruitment

Lou, Q., Hu, Y., Ma, Y. & Dong, Z., Jan 1 2019, In : American Journal of Physiology - Cell Physiology. 316, 1, p. C81-C91

Research output: Contribution to journalArticle

1 Scopus citations

Specific TBC Domain-Containing Proteins Control the ER-Golgi-Plasma Membrane Trafficking of GPCRs

Wei, Z., Zhang, M., Li, C., Huang, W., Fan, Y., Guo, J., Khater, M., Fukuda, M., Dong, Z., Hu, G. & Wu, G., Jul 9 2019, In : Cell Reports. 28, 2, p. 554-566.e4

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential

Yang, D., Livingston, M. J., Liu, Z., Dong, G., Zhang, M., Chen, J. K. & Dong, Z., Feb 1 2018, In : Cellular and Molecular Life Sciences. 75, 4, p. 669-688 20 p.

Research output: Contribution to journalReview article

33 Scopus citations
1 Scopus citations
3 Scopus citations

Embryonic Fate Mapping Uncovers the Critical Role of microRNAs in the Development of Epidermal γδ T Cells

Yao, Y., Liu, Q., Martin, C., Yin, C., Dong, Z., Mi, Q. S. & Zhou, L., Jan 2018, In : Journal of Investigative Dermatology. 138, 1, p. 236-239 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Endoplasmic reticulum stress in ischemic and nephrotoxic acute kidney injury

Yan, M., Shu, S., Guo, C., Tang, C. & Dong, Z., Jul 4 2018, In : Annals of Medicine. 50, 5, p. 381-390 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease

Shu, S., Zhu, J., Liu, Z., Tang, C., Cai, J. & Dong, Z., Nov 2018, In : EBioMedicine. 37, p. 269-280 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury

Li, F., Liu, Z., Tang, C., Cai, J. & Dong, Z., Jun 2018, In : FASEB Journal. 32, 6, p. 3423-3433 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells

Liu, J., Livingston, M. J., Dong, G., Tang, C., Su, Y., Wu, G., Yin, X. M. & Dong, Z., Mar 1 2018, In : Cell Death and Disease. 9, 3, 322.

Research output: Contribution to journalArticle

23 Scopus citations

HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers

Khambu, B., Huda, N., Chen, X., Antoine, D. J., Li, Y., Dai, G., Köhler, U. A., Zong, W. X., Waguri, S., Werner, S., Oury, T. D., Dong, Z. & Yin, X. M., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2419-2435 17 p.

Research output: Contribution to journalArticle

20 Scopus citations

Inflammation and outer blood-retina barrier (BRB) compromise following choroidal murine cytomegalovirus (MCMV) infections

Xu, J., Liu, X., Mo, J., Marshall, B., Perry, L., Dong, Z. & Zhang, M., May 18 2018, In : Molecular Vision. 24, p. 379-394 16 p.

Research output: Contribution to journalArticle

MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury

Wei, Q., Sun, H., Song, S., Liu, Y., Liu, P., Livingston, M. J., Wang, J., Liang, M., Mi, Q. S., Huo, Y., Nahman, N. S., Mei, C. & Dong, Z., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5448-5464 17 p.

Research output: Contribution to journalArticle

15 Scopus citations

Micro RNAs are required for Langerhans cell, skin- and lung-resident macrophage ontogeny

Yao, Y., Martin, C., Yin, C., Guo, C., Dong, Z., Zhou, L. & Mi, Q. S., Sep 2018, In : Journal of Allergy and Clinical Immunology. 142, 3, p. 976-978.e2

Research output: Contribution to journalArticle

1 Scopus citations

Neutrophil extracellular traps in ischemic AKI: new way to kill

Liu, J. & Dong, Z., Feb 2018, In : Kidney International. 93, 2, p. 303-305 3 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury

Wang, Y., Tang, C., Cai, J., Chen, G., Zhang, D., Zhang, Z. & Dong, Z., Nov 1 2018, In : Cell Death and Disease. 9, 11, 1113.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury

Tang, C., Han, H., Yan, M., Zhu, S., Liu, J., Liu, Z., He, L., Tan, J., Liu, Y., Liu, H., Sun, L., Duan, S., Peng, Y., Liu, F., Yin, X. M., Zhang, Z. & Dong, Z., May 4 2018, In : Autophagy. 14, 5, p. 880-897 18 p.

Research output: Contribution to journalArticle

43 Scopus citations

PKCδ-mediated Nox2 activation promotes fluid-phase pinocytosis of antigens by immature dendritic cells

Singla, B., Ghoshal, P., Lin, H., Wei, Q., Dong, Z. & Csányi, G., Mar 26 2018, In : Frontiers in immunology. 9, MAR, 537.

Research output: Contribution to journalArticle

6 Scopus citations

Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity

Sun, L., Liu, J., Yuan, Y., Zhang, I. & Dong, Z., Sep 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F469-F478

Research output: Contribution to journalArticle

3 Scopus citations

Rodent models of AKI-CKD transition

Fu, Y., Tang, C., Cai, J., Chen, G., Zhang, D. & Dong, Z., Oct 5 2018, In : American Journal of Physiology - Renal Physiology. 315, 4, p. F1098-F1106

Research output: Contribution to journalReview article

18 Scopus citations

Serum sclerostin in vascular calcification and clinical outcome in chronic kidney disease

Zeng, C., Guo, C., Cai, J., Tang, C. & Dong, Z., Mar 1 2018, In : Diabetes and Vascular Disease Research. 15, 2, p. 99-105 7 p.

Research output: Contribution to journalReview article

10 Scopus citations
4 Scopus citations