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2019

MiRNAs in Extracellular Vesicles from iPS-Derived Cardiac Progenitor Cells Effectively Reduce Fibrosis and Promote Angiogenesis in Infarcted Heart

Xuan, W., Wang, L., Xu, M., Weintraub, N. L. & Ashraf, M., Jan 1 2019, In : Stem Cells International. 2019, 3726392.

Research output: Contribution to journalArticle

Open Access
Fibrosis
Stem Cells
MicroRNAs
Cell- and Tissue-Based Therapy
Cardiac Myocytes
2 Citations (Scopus)
Exosomes
Endothelial cells
MicroRNAs
Stem Cells
Myocardial Infarction
2018
2 Citations (Scopus)

Cardiac progenitors induced from human induced pluripotent stem cells with cardiogenic small molecule effectively regenerate infarcted hearts and attenuate fibrosis

Xuan, W., Wang, Y., Tang, Y. L., Ali, A., Hu, H., Maienschein-Cline, M. & Ashraf, M., Jan 1 2018, In : Shock. 50, 6, p. 627-639 13 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Fibrosis
Stem Cells
MicroRNAs
MEF2 Transcription Factors
6 Citations (Scopus)
Clustered Regularly Interspaced Short Palindromic Repeats
Induced Pluripotent Stem Cells
Regeneration
Duchenne Muscular Dystrophy
Muscles
9 Citations (Scopus)

Regenerative therapy for cardiomyopathies

Wang, Z., Su, X., Ashraf, M., Kim, I. M., Weintraub, N. L., Jiang, M. & Tang, Y., Jan 1 2018, In : Journal of Cardiovascular Translational Research. 11, 5, p. 357-365 9 p.

Research output: Contribution to journalArticle

Cardiomyopathies
Heart Diseases
Stem Cells
Cardiovascular Diseases
Exosomes

Stem cell and gene-based approaches for cardiac repair

Elmadbouh, I. & Ashraf, M., Jan 27 2018, Design of Nanostructures for Versatile Therapeutic Applications. Elsevier, p. 31-96 66 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Stem cells
Gene therapy
Repair
Stem Cells
Genes
2017
69 Citations (Scopus)

Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis

Gong, M., Yu, B., Wang, J., Wang, Y., Liu, M., Paul, C., Millard, R. W., Xiao, D. S., Ashraf, M. & Xu, M., Jan 1 2017, In : Oncotarget. 8, 28, p. 45200-45212 13 p.

Research output: Contribution to journalArticle

Exosomes
MicroRNAs
Mesenchymal Stromal Cells
Human Umbilical Vein Endothelial Cells
Endothelial Cells
9 Citations (Scopus)
Phosphodiesterase Inhibitors
Mesenchymal Stromal Cells
Bone Marrow Cells
Cell Survival
Myocardium
4 Citations (Scopus)

The expression of smad signaling pathway in myocardium and potential therapeutic effects

Duan, Y., Zhu, W., Liu, M., Ashraf, M. & Xu, M., Jul 2017, In : Histology and Histopathology. 32, 7, p. 651-659 9 p.

Research output: Contribution to journalReview article

Smad Proteins
Therapeutic Uses
Myocardium
Bone Morphogenetic Proteins
Myocardial Infarction
2016
35 Citations (Scopus)

Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase

Okada, M., Kim, H. W., Matsu-Ura, K., Wang, Y. G., Xu, M. & Ashraf, M., Jan 1 2016, In : Stem Cells. 34, 1, p. 148-159 12 p.

Research output: Contribution to journalArticle

Telomerase
MicroRNAs
Mesenchymal Stromal Cells
Stem Cells
Cell Aging
2 Citations (Scopus)

Attenuation of teratoma formation by p27 overexpression in induced pluripotent stem cells

Matsu-Ura, T., Sasaki, H., Okada, M., Mikoshiba, K. & Ashraf, M., Feb 15 2016, In : Stem Cell Research and Therapy. 7, 1, 286.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Teratoma
Stem cells
Embryonic Stem Cells
Embryoid Bodies
3 Citations (Scopus)

Clusterin/Akt up-regulation is critical for GATA-4 mediated cytoprotection of mesenchymal stem cells against ischemia injury

Yu, B., Yang, Y., Liu, H., Gong, M., Millard, R. W., Wang, Y. G., Ashraf, M. & Xu, M., Mar 2016, In : PloS one. 11, 3, e0151542.

Research output: Contribution to journalArticle

Clusterin
Cytoprotection
ischemia
Stem cells
Mesenchymal Stromal Cells