Find Research Outputs

Search in all content

Filters for Scholarly Output

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017

Author

  • David J Fulton
2020

Origins of Hypertension in Obesity: Plain Vanilla(oid) or Multiple Flavors?

Fulton, D. J. R. & Stepp, D. W., Jan 1 2020, (Accepted/In press) In : Circulation. p. 1334-1337 4 p.

Research output: Contribution to journalReview article

2019
2 Scopus citations

Differential mechanisms of adenosine- and ATPγS-induced microvascular endothelial barrier strengthening

Bátori, R., Kumar, S., Bordán, Z., Cherian-Shaw, M., Kovács-Kása, A., MacDonald, J. A., Fulton, D. J. R., Erdődi, F. & Verin, A. D., May 2019, In : Journal of Cellular Physiology. 234, 5, p. 5863-5879 17 p.

Research output: Contribution to journalArticle

Disruption of Immune Homeostasis in Human Dendritic Cells via Regulation of Autophagy and Apoptosis by Porphyromonas gingivalis

Meghil, M. M., Tawfik, O. K., Elashiry, M., Rajendran, M., Arce, R. M., Fulton, D. J., Schoenlein, P. V. & Cutler, C. W., Sep 24 2019, In : Frontiers in immunology. 10, 2286.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Galectin-3: A Harbinger of Reactive Oxygen Species, Fibrosis, and Inflammation in Pulmonary Arterial Hypertension

Fulton, D. J. R., Li, X., Bordan, Z., Wang, Y., Mahboubi, K., Rudic, R. D., Haigh, S., Chen, F. & Barman, S. A., Nov 10 2019, In : Antioxidants and Redox Signaling. 31, 14, p. 1053-1069 17 p.

Research output: Contribution to journalReview article

3 Scopus citations

Galectin-3 is expressed in vascular smooth muscle cells and promotes pulmonary hypertension through changes in proliferation, apoptosis, and fibrosis

Barman, S. A., Li, X., Haigh, S., Kondrikov, D., Mahboubi, K., Bordan, Z., Stepp, D. W., Zhou, J., Wang, Y., Weintraub, D. S., Traber, P., Snider, W., Jonigk, D., Sullivan, J., Ryan Crislip, G., Butcher, J. T., Thompson, J., Su, Y., Chen, F. & Fulton, D. J. R., May 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 316, 5, p. L784-L797

Research output: Contribution to journalArticle

5 Scopus citations
3 Scopus citations

Leptin restores endothelial function via endothelial PPARγ-nox1-mediated mechanisms in a mouse model of congenital generalized lipodystrophy

Bruder-Nascimento, T., Faulkner, J. L., Haigh, S., Kennard, S., Antonova, G., Patel, V. S., Fulton, D. J. R., Chen, W. & De Chantemèle, E. J. B., Dec 1 2019, In : Hypertension. 74, 6, p. 1399-1408 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension

Cao, Y., Zhang, X., Wang, L., Yang, Q., Ma, Q., Xu, J., Wang, J., Kovacs, L., Ayon, R. J., Liu, Z., Zhang, M., Zhou, Y., Zeng, X., Xu, Y., Wang, Y., Fulton, D. J., Weintraub, N. L., Lucas, R., Dong, Z., Yuan, J. X. J. & 8 others, Sullivan, J. C., Meadows, L., Barman, S. A., Wu, C., Quan, J., Hong, M., Su, Y. & Huo, Y., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13394-13403 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Progesterone predisposes females to obesity-associated leptin-mediated endothelial dysfunction via upregulating endothelial mr (mineralocorticoid receptor) expression

Faulkner, J. L., Kennard, S., Huby, A. C., Antonova, G., Lu, Q., Jaffe, I. Z., Patel, V. S., Fulton, D. J. R. & Belin De Chantemèle, E. J., Sep 1 2019, In : Hypertension. 74, 3, p. 678-686 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations

The molecular regulation and functional roles of NOX5

Fulton, D. J. R., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 353-375 23 p. (Methods in Molecular Biology; vol. 1982).

Research output: Chapter in Book/Report/Conference proceedingChapter

Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation

Wen, T., Liu, J., He, X., Dong, K., Hu, G., Yu, L., Yin, Q., Osman, I., Peng, J., Zheng, Z., Xin, H., Fulton, D. J., Du, Q., Zhang, W. & Zhou, J., Dec 1 2019, In : Cell Death and Differentiation. 26, 12, p. 2790-2806 17 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Ablation of Myeloid ADK (Adenosine Kinase) Epigenetically Suppresses Atherosclerosis in ApoE-/- (Apolipoprotein e Deficient) Mice

Zhang, M., Zeng, X., Yang, Q., Xu, J., Liu, Z., Zhou, Y., Cao, Y., Zhang, X., An, X., Xu, Y., Huang, L., Han, Z., Wang, T., Wu, C., Fulton, D. J., Weintraub, N. L., Hong, M. & Huo, Y., Jan 1 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 12, p. 2780-2792 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Extracellular adenosine-induced Rac1 activation in pulmonary endothelium: Molecular mechanisms and barrier-protective role

Kovacs-Kasa, A., Kim, K. M., Cherian-Shaw, M., Black, S. M., Fulton, D. J. & Verin, A. D., Aug 2018, In : Journal of Cellular Physiology. 233, 8, p. 5736-5746 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Galectin-3 promotes vascular remodeling and contributes to pulmonary hypertension

Barman, S. A., Chen, F., Li, X., Haigh, S., Stepp, D. W., Kondrikov, D., Mahboubi, K., Bordan, Z., Traber, P., Su, Y. & Fulton, D. J. R., Jun 1 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 11, p. 1488-1492 5 p.

Research output: Contribution to journalLetter

7 Scopus citations

Hsp70 suppresses mitochondrial reactive oxygen species and preserves pulmonary microvascular barrier integrity following exposure to bacterial toxins

Li, X., Yu, Y., Gorshkov, B., Haigh, S., Bordan, Z., Weintraub, D., Rudic, R. D., Chakraborty, T., Barman, S. A., Verin, A. D., Su, Y., Lucas, R., Stepp, D. W., Chen, F. & Fulton, D. J., Jun 12 2018, In : Frontiers in immunology. 9, JUN, 1309.

Research output: Contribution to journalArticle

11 Scopus citations

Increased muscle mass protects against hypertension and renal injury in obesity

Butcher, J. T., Mintz, J. D., Larion, S., Qiu, S., Ruan, L., Fulton, D. J. & Stepp, D. W., Aug 1 2018, In : Journal of the American Heart Association. 7, 16, e009358.

Research output: Contribution to journalArticle

6 Scopus citations

Mechanisms of diabetes-induced endothelial cell senescence: Role of arginase 1

Shosha, E., Xu, Z., Priya Narayanan, S., Lemtalsi, T., Fouda, A. Y., Rojas, M., Xing, J., Fulton, D., William Caldwell, R. & Caldwell, R. B., Apr 17 2018, In : International journal of molecular sciences. 19, 4, 1215.

Research output: Contribution to journalArticle

5 Scopus citations
12 Scopus citations

Neurofibromin deficiency induces endothelial cell proliferation and retinal neovascularization

Zhang, H., Hudson, F. Z., Xu, Z., Tritz, R., Rojas, M., Patel, C., Haigh, S. B., Bordán, Z., Ingram, D. A., Fulton, D. J., Weintraub, N. L., Caldwell, R. B. & Stansfield, B. K., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2520-2528 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis

Yang, Q., Xu, J., Ma, Q., Liu, Z., Varadarajan, S., Cao, Y., Wang, L., Zeng, X., Zhou, Y., Zhang, M., Xu, Y., Wang, Y., Weintraub, N. L., Zhang, C., Fukai, T., Wu, C., Huang, L., Han, Z., Wang, T., Fulton, D. J. & 2 others, Hong, M. & Huo, Y., Dec 1 2018, In : Nature communications. 9, 1, 4667.

Research output: Contribution to journalArticle

8 Scopus citations

Vasodilator dysfunction and oligodendrocyte dysmaturation in aging white matter

Bagi, Z., Brandner, D. D., Le, P., McNeal, D. W., Gong, X., Dou, H., Fulton, D. J., Beller, A., Ngyuen, T., Larson, E. B., Montine, T. J., Keene, C. D. & Back, S. A., Jan 2018, In : Annals of Neurology. 83, 1, p. 142-152 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Adventitial fibroblast Nox4 expression and ROS signaling in pulmonary arterial hypertension

Barman, S. A. & Fulton, D., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 1-11 11 p. (Advances in Experimental Medicine and Biology; vol. 967).

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity

Yiew, N. K. H., Chatterjee, T. K., Tang, Y. L., Pellenberg, R., Stansfield, B. K., Bagi, Z., Fulton, D. J., Stepp, D. W., Chen, W., Patel, V., Kamath, V. M., Litwin, S. E., Hui, D. Y., Rudich, S. M., Kim, H. W. & Weintraub, N. L., Apr 14 2017, In : Journal of Biological Chemistry. 292, 15, p. 6312-6324 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Beyond impressions how altered shear stress connects hypoxic signaling to endothelial inflammation

Li, X., Weintraub, D. S. & Fulton, D. J., Jan 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 11, p. 1987-1989 3 p.

Research output: Contribution to journalReview article

4 Scopus citations

Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery

Shang, X., Pati, P., Anea, C. B., Fulton, D. J. R. & Rudic, R. D., Jan 1 2017, In : Journal of Vascular Research. 53, 5-6, p. 269-278 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Effect of myostatin deletion on cardiac and microvascular function

Butcher, J. T., Ali, M. I., Ma, M. W., McCarthy, C. G., Islam, B. N., Fox, L. G., Mintz, J. D., Larion, S., Fulton, D. J. & Stepp, D. W., Dec 2017, In : Physiological reports. 5, 23, e13525.

Research output: Contribution to journalArticle

6 Scopus citations

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis

Liu, Z., Yan, S., Wang, J., Xu, Y., Wang, Y., Zhang, S., Xu, X., Yang, Q., Zeng, X., Zhou, Y., Gu, X., Lu, S., Fu, Z., Fulton, D. J., Weintraub, N. L., Caldwell, R. B., Zhang, W., Wu, C., Liu, X. L., Chen, J. F. & 10 others, Ahmad, A., Kaddour-Djebbar, I., Al-Shabrawey, M., Li, Q., Jiang, X., Sun, Y., Sodhi, A., Smith, L., Hong, M. & Huo, Y., Dec 1 2017, In : Nature communications. 8, 1, 584.

Research output: Contribution to journalArticle

20 Scopus citations

Epigenetic regulation of interleukin 6 by histone acetylation in macrophages and its role in paraquat-induced pulmonary fibrosis

Hu, L., Yu, Y., Huang, H., Fan, H., Hu, L., Yin, C., Li, K., Fulton, D. J. & Chen, F., Jan 30 2017, In : Frontiers in immunology. 7, JAN, 696.

Research output: Contribution to journalArticle

31 Scopus citations

Epithelial sodium channel-α mediates the protective effect of the TNF-derived TIP peptide in pneumolysin-induced endothelial barrier dysfunction

Czikora, I., Alli, A. A., Sridhar, S., Matthay, M. A., Pillich, H., Hudel, M., Berisha, B., Gorshkov, B. A., Romero Lucas, M. J., Gonzales, J. N., Wu, G., Huo, Y., Su, Y., Verin, A. D., Fulton, D. J., Chakraborty, T., Eaton, D. C. & Lucas, R., Jul 21 2017, In : Frontiers in immunology. 8, JUL, 842.

Research output: Contribution to journalArticle

12 Scopus citations

Genetic deletion of NADPH oxidase 1 rescues microvascular function in mice with metabolic disease

Thompson, J. A., Larion, S., Mintz, J. D., Belin De Chantemèle, E. J., Fulton, D. J. & Stepp, D. W., Aug 1 2017, In : Circulation research. 121, 5, p. 502-511 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis

Xu, Y., Wang, Y., Yan, S., Zhou, Y., Yang, Q., Pan, Y., Zeng, X., An, X., Liu, Z., Wang, L., Xu, J., Cao, Y., Fulton, D. J., Weintraub, N. L., Bagi, Z., Hoda, MD. N., Wang, X., Li, Q., Hong, M., Jiang, X. & 4 others, Boison, D., Weber, C., Wu, C. & Huo, Y., Sep 2017, In : EMBO Molecular Medicine. 9, 9, p. 1263-1278 16 p.

Research output: Contribution to journalArticle

22 Scopus citations

Nox2-Mediated PI3K and Cofilin Activation Confers Alternate Redox Control of Macrophage Pinocytosis

Ghoshal, P., Singla, B., Lin, H., Feck, D. M., Cantu-Medellin, N., Kelley, E. E., Haigh, S., Fulton, D. & Csányi, G., Jun 1 2017, In : Antioxidants and Redox Signaling. 26, 16, p. 902-916 15 p.

Research output: Contribution to journalReview article

9 Scopus citations

Reactive oxygen and nitrogen species in the development of pulmonary hypertension

Fulton, D. J. R., Li, X., Bordan, Z., Haigh, S., Bentley, A., Chen, F. & Barman, S. A., Sep 2017, In : Antioxidants. 6, 3, 54.

Research output: Contribution to journalReview article

29 Scopus citations

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation

Xu, Y., Wang, Y., Yan, S., Yang, Q., Zhou, Y., Zeng, X., Liu, Z., An, X., Flores Toque, H. A., Dong, Z., Jiang, X., Fulton, D. J., Weintraub, N. L., Li, Q., Bagi, Z., Hong, M., Boison, D., Wu, C. & Huo, Y., Dec 1 2017, In : Nature communications. 8, 1, 986.

Research output: Contribution to journalArticle

19 Scopus citations

RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins

Chen, F., Wang, Y., Rafikov, R., Haigh, S., Kumar, S., Rafikova, O., Lucas, R., Verin, A. D., Black, S. M. & Fulton, D. J. R., Mar 1 2017, In : Biochemical Pharmacology. 127, p. 34-45 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Role of Adipose Tissue Endothelial ADAM17 in Age-Related Coronary Microvascular Dysfunction

Dou, H., Feher, A., Davila, A. C., Romero, M. J., Patel, V. S., Kamath, V. M., Gooz, M. B., Rudic, R. D., Lucas, R., Fulton, D. J., Weintraub, N. L. & Bagi, Z., Jun 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 6, p. 1180-1193 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Role of myeloperoxidase in abdominal aortic aneurysm formation: Mitigation by taurine

Kim, H. W., Blomkalns, A. L., Ogbi, M., Thomas, M., Gavrila, D., Neltner, B. S., Cassis, L. A., Thompson, R. W., Weiss, R. M., Lindower, P. D., Blanco, V. M., McCormick, M. L., Daugherty, A., Fu, X., Hazen, S. L., Stansfield, B. K., Huo, Y., Fulton, D. J., Chatterjee, T. & Weintraub, N. L., Dec 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 6, p. H1168-H1179

Research output: Contribution to journalArticle

12 Scopus citations