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• 2020

  Editorial: The Tumor Microenvironment: Recent Advances and Novel Therapeutic Approaches

  Korkaya, H. & Orsulic, S., Sep 17 2020, In: Frontiers in Cell and Developmental Biology. 8, 586176.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal

  Bridges, A. E., Ramachandran, S., Pathania, R., Parwal, U., Lester, A., Rajpurohit, P., Morera, D. S., Patel, N., Singh, N., Korkaya, H., Manicassamy, S., Prasad, P. D., Lokeshwar, V. B., Lokeshwar, B. L., Ganapathy, V. & Thangaraju, M., Sep 15 2020, In: Cancer Research. 80, 18, p. 3855-3866 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Rad51 Recombinase
  • Protein Deficiency
  • Cell Self Renewal
  • Breast Neoplasms
  • Growth

• Short-term diet restriction but not alternate day fasting prevents cisplatin-induced nephrotoxicity in mice

  Gunebakan, E., Yalcin, E., Dulger, E. C., Yigitbasi, A., Ates, N., Caglayan, A., Beker, M. C., Sahin, K., Korkaya, H. & Kilic, E., Feb 1 2020, In: Biomedicines. 8, 2, 23.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nutrition
  • Cisplatin
  • Fasting
  • Diet
  • Phosphorylation

• Therapeutic utility of immunosuppressive TREM2+ macrophages: an important step forward in potentiating the immune checkpoint inhibitors

  Alkan, F. K. & Korkaya, H., Dec 2020, In: Signal Transduction and Targeted Therapy. 5, 1, 264.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2019

  Correction: The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20 (Oncogene, (2019), 38, 4, (469-482), 10.1038/s41388-018-0472-0)

  Lee, E., Ouzounova, M., Piranlioglu, R., Ma, M. T., Guzel, M., Marasco, D., Chadli, A., Gestwicki, J. E., Cowell, J. K., Wicha, M. S., Hassan, K. A. & Korkaya, H., Jul 11 2019, In: Oncogene. 38, 28, 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Financial Management
  • Oncogenes
  • Breast Neoplasms
  • Laboratory Animals
  • Genomics

• Dietary myo-inositol chemoprevents lung carcinogenesis via boosting immune system in Kras mouse model

  Piranlioglu, R., Korkaya, H. & Hassan, K. A., 2019, In: Journal of Thoracic Disease. 11, 3, p. 632-635 4 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Scopus citations

• Plasticity and potency of mammary stem cell subsets during mammary gland development

  Lee, E., Piranlioglu, R., Wicha, M. S. & Korkaya, H., May 1 2019, In: International journal of molecular sciences. 20, 9, 2357.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • mammary glands
  • Stem cells
  • stem cells
  • Human Mammary Glands
  • set theory
  3 Scopus citations

• Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

  Piranlioglu, R., Lee, E. M., Ouzounova, M., Bollag, R. J., Vinyard, A., Arbab, A. S., Marasco, D., Guzel, M., Cowell, J. K., Thangaraju, M., Chadli, A., Hassan, K. A., Wicha, M. S., Celis, E. & Korkaya, H., Dec 1 2019, In: Nature communications. 10, 1, 1430.

  Research output: Contribution to journal › Article › peer-review

  • immunity
  • mice
  • Tumors
  • Cells
  • tumors
  18 Scopus citations

• The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis

  Eisa, N. H., Jilani, Y., Kainth, K., Redd, P., Lu, S., Bougrine, O., Sater, H. A., Patwardhan, C. A., Shull, A., Shi, H., Liu, K., Elsherbiny, N. M., Eissa, L. A., El-Shishtawy, M. M., Horuzsko, A., Bollag, R., Maihle, N., Roig, J., Korkaya, H., Cowell, J. K. & 1 others, Chadli, A., Apr 5 2019, In: Journal of Biological Chemistry. 294, 14, p. 5246-5260 15 p.

  Research output: Contribution to journal › Article › peer-review

  • NIMA-Related Kinases
  • Myosins
  • Phosphotransferases
  • Carcinogenesis
  • Cell proliferation
  7 Scopus citations

• The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20

  Lee, E., Ouzounova, M., Piranlioglu, R., Ma, M. T., Guzel, M., Marasco, D., Chadli, A., Gestwicki, J. E., Cowell, J. K., Wicha, M. S., Hassan, K. A. & Korkaya, H., Jan 24 2019, In: Oncogene. 38, 4, p. 469-482 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Breast Neoplasms
  • Cell Death
  • Triple Negative Breast Neoplasms
  • Heterografts
  • Cell Line
  12 Scopus citations
• 2018

  Mimetics of suppressor of cytokine signaling 3: Novel potential therapeutics in triple breast cancer

  La Manna, S., Lee, E., Ouzounova, M., Di Natale, C., Novellino, E., Merlino, A., Korkaya, H. & Marasco, D., Nov 1 2018, In: International Journal of Cancer. 143, 9, p. 2177-2186 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Triple Negative Breast Neoplasms
  • Breast Neoplasms
  • Cytokines
  • Neoplasms
  • Peptides
  10 Scopus citations

• SALL1 expression in acute myeloid leukemia

  Salman, H., Shuai, X., Nguyen-Lefebvre, A. T., Giri, B., Ren, M., Rauchman, M., Robbins, L., Hou, W., Korkaya, H. & Ma, Y., Jan 26 2018, In: Oncotarget. 9, 7, p. 7442-7452 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hematopoietic Stem Cells
  • Acute Myeloid Leukemia
  • Stem Cells
  • Leukemia
  • Bone Marrow
  1 Scopus citations

• SRC increases MYC mRNA expression in estrogen receptor-positive breast cancer via mRNA stabilization and inhibition of p53 function

  Abdullah, C., Korkaya, H., Iizuka, S. & Courtneidge, S. A., Mar 1 2018, In: Molecular and Cellular Biology. 38, 6, e00463-17.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Breast Neoplasms
  • Messenger RNA
  • Estrogens
  • Gene Amplification
  3 Scopus citations

• Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2⁺ Breast Cancer

  Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In: Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Small Interfering RNA
  • Breast Neoplasms
  • Nucleotide Aptamers
  • Antibodies
  • Nucleic Acids
  30 Scopus citations

• The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer

  Kadi, N. E., Wang, L., Davis, A., Korkaya, H., Cooke, A., Vadnala, V., Brown, N. A., Betz, B. L., Cascalho, M., Kalemkerian, G. P. & Hassan, K. A., Dec 15 2018, In: Cancer Research. 78, 24, p. 6728-6735 8 p.

  Research output: Contribution to journal › Article › peer-review

  • AICDA (activation-induced cytidine deaminase)
  • 5-Methylcytosine
  • Deamination
  • Protein-Tyrosine Kinases
  • Lung Neoplasms
  14 Scopus citations

• Thymoquinone prevents cisplatin neurotoxicity in primary DRG neurons

  Üstün, R., Oğuz, E. K., Şeker, A. & Korkaya, H., Dec 2018, In: NeuroToxicology. 69, p. 68-76 9 p.

  Research output: Contribution to journal › Article › peer-review

  • thymoquinone
  • Spinal Ganglia
  • Neurons
  • Cisplatin
  • Chemotherapy
  6 Scopus citations

• Thymoquinone protects DRG neurons from axotomy-induced cell death

  Üstün, R., Oğuz, E. K., Şeker, A. & Korkaya, H., Nov 2 2018, In: Neurological Research. 40, 11, p. 930-937 8 p.

  Research output: Contribution to journal › Article › peer-review

  • thymoquinone
  • Axotomy
  • Spinal Ganglia
  • Cell Death
  • Peripheral Nerve Injuries
  4 Scopus citations
• 2017

  HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model

  Borin, T. F., Shankar, A., Angara, K., Rashid, M. H., Jain, M., Iskander, A., Ara, R., Lebedyeva, I., Korkaya, H., Achyut, B. R. & Arbab, A. S., Jun 2017, In: PloS one. 12, 6, 0178830.

  Research output: Contribution to journal › Article › peer-review

  • metastasis
  • breast neoplasms
  • Tumors
  • animal models
  • lungs
  10 Scopus citations

• Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

  Ouzounova, M., Lee, E., Piranlioglu, R., El Andaloussi, A., Kolhe, R., Demirci, M. F., Marasco, D., Asm, I., Chadli, A., Hassan, K. A., Thangaraju, M., Zhou, G., Arbab, A. S., Cowell, J. K. & Korkaya, H., 2017, In: Nature communications. 8, 14979.

  Research output: Contribution to journal › Article › peer-review

  • suppressors
  • Myeloid-Derived Suppressor Cells
  • Tumors
  • tumors
  • Plasticity
  116 Scopus citations

• Promoter methylation modulates indoleamine 2,3-dioxygenase 1 induction by activated T cells in human breast cancers

  Noonepalle, S. K., Gu, F., Lee, E. J., Choi, J. H., Han, Q., Kim, J., Ouzounova, M., Shull, A. Y., Pei, L., Hsu, P. Y., Kolhe, R., Shi, F., Choi, J., Chiou, K., Huang, T. H. M., Korkaya, H., Deng, L., Xin, H. B., Huang, S., Thangaraju, M. & 5 others, Sreekumar, A., Ambs, S., Tang, S. C., Munn, D. H. & Shi, H., Apr 2017, In: Cancer Immunology Research. 5, 4, p. 330-344 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Methylation
  • Breast Neoplasms
  • Triple Negative Breast Neoplasms
  • T-Lymphocytes
  13 Scopus citations