A 10-Year Experience with Magnetic Source Imaging in the Guidance of Epilepsy Surgery

Joseph R. Smith, Don W. King, Yong D Park, Anthony M Murro, Gregory P Lee, Patrick D. Jenkins

Research output: Contribution to journalArticle

8 Scopus citations


Magnetic source imaging (MSI) of interictal epileptiform dipoles was studied in 100 epilepsy surgery candidates. Sixty underwent surgery. MSI epileptiform data were classified as focal, regional, multifocal, scattered or none. Resections of MSI epileptiform foci were classified as extensive (EXT) versus partial or none (P/N). MSI interictal epileptiform dipoles were found in 22 of 27 anterior temporal (ATL) cases, and in 31 of 33 extratemporal (XMT) cases. Of 10 EXT ATL cases, 5 (50%) were seizure free (SF). Of 12 P/N ATL cases, 7 (58%) were SF. Of 10 nonlesional EXT XMT resections, 8 (80%) were SF. Of 10 nonlesional P/N XMT resections, 1 (10%) was SF. Neither focality of MSI data or spatial agreement of electrographic and MSI data significantly affected outcomes.

Original languageEnglish (US)
Pages (from-to)14-17
Number of pages4
JournalStereotactic and Functional Neurosurgery
Issue number1-4
Publication statusPublished - Dec 1 2003



  • Anterior temporal resections
  • Extratemporal resections
  • Magnetic source imaging
  • Magnetoencephalography

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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