A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood

Zhibin Li, Harold Snieder, Gregory A Harshfield, Frank A. Treiber, Xiaoling Wang

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

This study evaluates the tracking stability of office blood pressure (BP), ambulatory BP (ABP), BP variability (BPV) and nocturnal BP drops (dipping) from childhood to early adulthood, and their dependence on ethnicity, gender and family history (FH) of essential hypertension (EH). Generalized estimating equations (GEEs) were used to estimate tracking coefficients for 295 European Americans and 252 African Americans, with a maximum of 12 measurements over a 15-year period. Office BP and ABP had moderate-to-relatively high tracking coefficients (r=0.30-0.59; P≤0.001). Twenty-four hour readings tracked better than office readings for diastolic BP (DBP; 0.57 vs. 0.46, P=1.72 × 10-6) and pulse pressure (PP) (0.59 vs. 0.51, P=2.70 × 10-4), and equally well for systolic BP (SBP; 0.55 vs. 0.54, P=0.805). Daytime readings tracked better than their night-time counterparts for SBP (0.50 vs. 0.37, P=7.62 × 10-13), DBP (0.49 vs. 0.30, P=7.98 × 10-32) and PP (0.55 vs. 0.50, P=0.0061). All BPV (r=0.08-0.28; P<0.001) and dipping measures (r=0.07-0.12; odds ratio, 1.60-1.73; P<0.001) had low tracking coefficients. Males had significantly higher tracking stability for office SBP, DBP and ambulatory PP than females (P<0.01). Subjects with a positive FH of EH had significantly higher tracking stability for daytime and night-time DBP and dipping indexed by continuous variables than those with a negative FH (P<0.001). No significant ethnic differences were observed. The high tracking stability of 24-h ABP highlights the importance of using ambulatory BP monitoring in both research and clinical settings.

Original languageEnglish (US)
Pages (from-to)404-410
Number of pages7
JournalHypertension Research
Volume32
Issue number5
DOIs
StatePublished - Aug 12 2009

Fingerprint

Longitudinal Studies
Blood Pressure
Reading
Ambulatory Blood Pressure Monitoring
African Americans
Odds Ratio

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood. / Li, Zhibin; Snieder, Harold; Harshfield, Gregory A; Treiber, Frank A.; Wang, Xiaoling.

In: Hypertension Research, Vol. 32, No. 5, 12.08.2009, p. 404-410.

Research output: Contribution to journalArticle

@article{ef6ac64bdd934694a309a7829e9468b3,
title = "A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood",
abstract = "This study evaluates the tracking stability of office blood pressure (BP), ambulatory BP (ABP), BP variability (BPV) and nocturnal BP drops (dipping) from childhood to early adulthood, and their dependence on ethnicity, gender and family history (FH) of essential hypertension (EH). Generalized estimating equations (GEEs) were used to estimate tracking coefficients for 295 European Americans and 252 African Americans, with a maximum of 12 measurements over a 15-year period. Office BP and ABP had moderate-to-relatively high tracking coefficients (r=0.30-0.59; P≤0.001). Twenty-four hour readings tracked better than office readings for diastolic BP (DBP; 0.57 vs. 0.46, P=1.72 × 10-6) and pulse pressure (PP) (0.59 vs. 0.51, P=2.70 × 10-4), and equally well for systolic BP (SBP; 0.55 vs. 0.54, P=0.805). Daytime readings tracked better than their night-time counterparts for SBP (0.50 vs. 0.37, P=7.62 × 10-13), DBP (0.49 vs. 0.30, P=7.98 × 10-32) and PP (0.55 vs. 0.50, P=0.0061). All BPV (r=0.08-0.28; P<0.001) and dipping measures (r=0.07-0.12; odds ratio, 1.60-1.73; P<0.001) had low tracking coefficients. Males had significantly higher tracking stability for office SBP, DBP and ambulatory PP than females (P<0.01). Subjects with a positive FH of EH had significantly higher tracking stability for daytime and night-time DBP and dipping indexed by continuous variables than those with a negative FH (P<0.001). No significant ethnic differences were observed. The high tracking stability of 24-h ABP highlights the importance of using ambulatory BP monitoring in both research and clinical settings.",
author = "Zhibin Li and Harold Snieder and Harshfield, {Gregory A} and Treiber, {Frank A.} and Xiaoling Wang",
year = "2009",
month = "8",
day = "12",
doi = "10.1038/hr.2009.32",
language = "English (US)",
volume = "32",
pages = "404--410",
journal = "Hypertension Research",
issn = "0916-9636",
publisher = "Nature Publishing Group",
number = "5",

}

TY - JOUR

T1 - A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood

AU - Li, Zhibin

AU - Snieder, Harold

AU - Harshfield, Gregory A

AU - Treiber, Frank A.

AU - Wang, Xiaoling

PY - 2009/8/12

Y1 - 2009/8/12

N2 - This study evaluates the tracking stability of office blood pressure (BP), ambulatory BP (ABP), BP variability (BPV) and nocturnal BP drops (dipping) from childhood to early adulthood, and their dependence on ethnicity, gender and family history (FH) of essential hypertension (EH). Generalized estimating equations (GEEs) were used to estimate tracking coefficients for 295 European Americans and 252 African Americans, with a maximum of 12 measurements over a 15-year period. Office BP and ABP had moderate-to-relatively high tracking coefficients (r=0.30-0.59; P≤0.001). Twenty-four hour readings tracked better than office readings for diastolic BP (DBP; 0.57 vs. 0.46, P=1.72 × 10-6) and pulse pressure (PP) (0.59 vs. 0.51, P=2.70 × 10-4), and equally well for systolic BP (SBP; 0.55 vs. 0.54, P=0.805). Daytime readings tracked better than their night-time counterparts for SBP (0.50 vs. 0.37, P=7.62 × 10-13), DBP (0.49 vs. 0.30, P=7.98 × 10-32) and PP (0.55 vs. 0.50, P=0.0061). All BPV (r=0.08-0.28; P<0.001) and dipping measures (r=0.07-0.12; odds ratio, 1.60-1.73; P<0.001) had low tracking coefficients. Males had significantly higher tracking stability for office SBP, DBP and ambulatory PP than females (P<0.01). Subjects with a positive FH of EH had significantly higher tracking stability for daytime and night-time DBP and dipping indexed by continuous variables than those with a negative FH (P<0.001). No significant ethnic differences were observed. The high tracking stability of 24-h ABP highlights the importance of using ambulatory BP monitoring in both research and clinical settings.

AB - This study evaluates the tracking stability of office blood pressure (BP), ambulatory BP (ABP), BP variability (BPV) and nocturnal BP drops (dipping) from childhood to early adulthood, and their dependence on ethnicity, gender and family history (FH) of essential hypertension (EH). Generalized estimating equations (GEEs) were used to estimate tracking coefficients for 295 European Americans and 252 African Americans, with a maximum of 12 measurements over a 15-year period. Office BP and ABP had moderate-to-relatively high tracking coefficients (r=0.30-0.59; P≤0.001). Twenty-four hour readings tracked better than office readings for diastolic BP (DBP; 0.57 vs. 0.46, P=1.72 × 10-6) and pulse pressure (PP) (0.59 vs. 0.51, P=2.70 × 10-4), and equally well for systolic BP (SBP; 0.55 vs. 0.54, P=0.805). Daytime readings tracked better than their night-time counterparts for SBP (0.50 vs. 0.37, P=7.62 × 10-13), DBP (0.49 vs. 0.30, P=7.98 × 10-32) and PP (0.55 vs. 0.50, P=0.0061). All BPV (r=0.08-0.28; P<0.001) and dipping measures (r=0.07-0.12; odds ratio, 1.60-1.73; P<0.001) had low tracking coefficients. Males had significantly higher tracking stability for office SBP, DBP and ambulatory PP than females (P<0.01). Subjects with a positive FH of EH had significantly higher tracking stability for daytime and night-time DBP and dipping indexed by continuous variables than those with a negative FH (P<0.001). No significant ethnic differences were observed. The high tracking stability of 24-h ABP highlights the importance of using ambulatory BP monitoring in both research and clinical settings.

UR - http://www.scopus.com/inward/record.url?scp=68249158279&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=68249158279&partnerID=8YFLogxK

U2 - 10.1038/hr.2009.32

DO - 10.1038/hr.2009.32

M3 - Article

C2 - 19325561

AN - SCOPUS:68249158279

VL - 32

SP - 404

EP - 410

JO - Hypertension Research

JF - Hypertension Research

SN - 0916-9636

IS - 5

ER -