A benzotriazole-mediated route to protected marine-derived hetero-2,5-diketopiperazines containing proline

Medicine & Life Sciences

• 2,5-dioxopiperazine 100%
• benzotriazole 90%
• Diketopiperazines 56%
• Proline 51%
• triethylamine 25%
• Cyclization 24%
• Disulfides 17%
• Biological Products 15%
• Libraries 14%

Chemical Compounds

• 2,5-diketopiperazines 78%
• Proline 49%
• Proline Derivative 36%
• Triethylamine 23%
• Occurrence in Nature 20%
• Disulfide 19%
• Cyclization Reaction 18%

Physics & Astronomy

• disulfides 61%
• routes 39%
• activation 38%
• preparation 35%
• synthesis 34%
• products 30%