A gene-based approach for testing association of rare alleles

Research output: Contribution to journalArticle

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Abstract

Rare genetic variants have been shown to be important to the susceptibility of common human diseases. Methods for detecting association of rare genetic variants are drawing much attention. In this report, we applied a gene-based approach to the 200 simulated data sets of unrelated individuals. The test can detect the association of some genes with multiple rare variants.

Original languageEnglish (US)
Article numberS7
JournalBMC Proceedings
Volume5
Issue numberSUPPL. 9
DOIs
StatePublished - Dec 1 2011

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Genes
Alleles
Testing
Datasets

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

A gene-based approach for testing association of rare alleles. / Xu, Hongyan; George, Varghese.

In: BMC Proceedings, Vol. 5, No. SUPPL. 9, S7, 01.12.2011.

Research output: Contribution to journalArticle

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