A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6

Marsha E. O'Neill, Jacquie Marietta, Darryl Nishimura, Sigrid Wayne, Guy Van Camp, Lut Van Laer, Clelia Negrini, Edward R. Wilcox, Achih Chen, Kunihiro Fukushima, Li Ni, Val C. Sheffield, Richard J.H. Smith

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

Late-onset non-syndromic hearing impairment is the most common type of neurological dysfunction in the elderly. It can be either acquired or inherited, although the relative impact of heredity on this type of loss is not known. To date, nine different genes have been localized, but none has been cloned. Using an extended American family in which a gene for autosomal dominant late-onset non-syndromic hearing impairment is segregating, we have identified a new locus, DFNA10, on chromosome 6.

Original languageEnglish (US)
Pages (from-to)853-856
Number of pages4
JournalHuman Molecular Genetics
Volume5
Issue number6
DOIs
StatePublished - Jun 1996
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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