A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique

Jian Yue Jin, Bo Zhao, Joseph M. Kaminski, Ning Wen, Yimei Huang, John Vender, Indrin J. Chetty

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

This study presents a MLC-based, 3D grid-therapy technique with characteristics of both 3D-conformal-radiotherapy and grid-therapy. It generates a brachytherapy-like dose distribution, with D50% of 20, 9.8, 5.4 and 2.9-Gy, for the spheres, target, 1 cm-outershell and 2 cm-outershell, respectively. It may provide a strategy to deliver ablative doses to large tumors safely.

Original languageEnglish (US)
Pages (from-to)483-486
Number of pages4
JournalRadiotherapy and Oncology
Volume117
Issue number3
DOIs
StatePublished - Dec 1 2015

Keywords

  • Ablative radiation
  • Film dosimetry
  • Grid therapy
  • Immune-response
  • Spatially fractionated radiotherapy

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Radiology Nuclear Medicine and imaging

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