A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.

Jennifer C. Naylor, Trygve R. Dolber, Jennifer L. Strauss, Jason D. Kilts, Timothy J. Strauman, Daniel W. Bradford, Steven T. Szabo, Nagy A. Youssef, Kathryn M. Connor, Jonathan R.T. Davidson, Christine E. Marx

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk for suicidality, depression, and functional impairment. We thus conducted a small (N=12) pilot randomized controlled trial (RCT) with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era veterans. Hospital Anxiety and Depression Scale (HADS) scores improved by 30.4% in the paroxetine group. Paroxetine may have promise for subthreshold PTSD. Published by Elsevier Ireland Ltd.

Original languageEnglish (US)
Pages (from-to)318-320
Number of pages3
JournalUnknown Journal
Volume206
Issue number2-3
DOIs
StatePublished - Apr 30 2013

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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    Naylor, J. C., Dolber, T. R., Strauss, J. L., Kilts, J. D., Strauman, T. J., Bradford, D. W., Szabo, S. T., Youssef, N. A., Connor, K. M., Davidson, J. R. T., & Marx, C. E. (2013). A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans. Unknown Journal, 206(2-3), 318-320. https://doi.org/10.1016/j.psychres.2012.11.008