A pilot study to assess residential endotoxin and blood IgE in a group of pregnant women from Trujillo, Peru

Molly C. Visser, Dennis Randall Ownby, Manuel Aguilar-Villalobos, Larry L. Needham, Luke P. Naeher

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective: This November 2003 pilot study investigates the correlation between serum IgE and residential endotoxin levels from a group of 18 pregnant women living in Trujillo, Peru, and investigates the impact of the demographic and lifestyle factors of this group on the IgE and endotoxin levels measured. Methods: Serum samples were collected from 19 subjects and analyzed for IgE. Dust samples were collected from the mattresses of 18 subjects and measured for endotoxin levels. A questionnaire was used to obtain demographic, socioeconomic, and lifestyle information for each subject. Results: Geometric means for IgE and endotoxin were 246.8 (GSD = 4.3, n = 19) IU/mL and 66.5 EU/mg (GSD = 1.7, n = 18), respectively. Log-transformed IgE and endotoxin were not correlated (R2 = 0.02; p = 0.60). Conclusions: Residential endotoxin and serum IgE were not correlated in this group. Potential selection bias and sample size are major limitations of the study. However, 74% (14/19) of the subjects in this study had an IgE over 100 IU/mL, a level generally considered elevated.

Original languageEnglish (US)
Pages (from-to)147-150
Number of pages4
JournalEnvironment International
Volume33
Issue number2
DOIs
StatePublished - Jan 1 2007

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serum
blood
lifestyle
dust
woman
method
socioeconomics

Keywords

  • Developing world
  • Endotoxin
  • IgE
  • Peru
  • Pregnant women

ASJC Scopus subject areas

  • Environmental Science(all)

Cite this

A pilot study to assess residential endotoxin and blood IgE in a group of pregnant women from Trujillo, Peru. / Visser, Molly C.; Ownby, Dennis Randall; Aguilar-Villalobos, Manuel; Needham, Larry L.; Naeher, Luke P.

In: Environment International, Vol. 33, No. 2, 01.01.2007, p. 147-150.

Research output: Contribution to journalArticle

Visser, Molly C. ; Ownby, Dennis Randall ; Aguilar-Villalobos, Manuel ; Needham, Larry L. ; Naeher, Luke P. / A pilot study to assess residential endotoxin and blood IgE in a group of pregnant women from Trujillo, Peru. In: Environment International. 2007 ; Vol. 33, No. 2. pp. 147-150.
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