Abstract
Objective: This November 2003 pilot study investigates the correlation between serum IgE and residential endotoxin levels from a group of 18 pregnant women living in Trujillo, Peru, and investigates the impact of the demographic and lifestyle factors of this group on the IgE and endotoxin levels measured. Methods: Serum samples were collected from 19 subjects and analyzed for IgE. Dust samples were collected from the mattresses of 18 subjects and measured for endotoxin levels. A questionnaire was used to obtain demographic, socioeconomic, and lifestyle information for each subject. Results: Geometric means for IgE and endotoxin were 246.8 (GSD = 4.3, n = 19) IU/mL and 66.5 EU/mg (GSD = 1.7, n = 18), respectively. Log-transformed IgE and endotoxin were not correlated (R2 = 0.02; p = 0.60). Conclusions: Residential endotoxin and serum IgE were not correlated in this group. Potential selection bias and sample size are major limitations of the study. However, 74% (14/19) of the subjects in this study had an IgE over 100 IU/mL, a level generally considered elevated.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 147-150 |
| Number of pages | 4 |
| Journal | Environment International |
| Volume | 33 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 2007 |
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Keywords
- Developing world
- Endotoxin
- IgE
- Peru
- Pregnant women
ASJC Scopus subject areas
- Environmental Science(all)
Cite this
A pilot study to assess residential endotoxin and blood IgE in a group of pregnant women from Trujillo, Peru. / Visser, Molly C.; Ownby, Dennis Randall; Aguilar-Villalobos, Manuel; Needham, Larry L.; Naeher, Luke P.
In: Environment International, Vol. 33, No. 2, 01.01.2007, p. 147-150.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A pilot study to assess residential endotoxin and blood IgE in a group of pregnant women from Trujillo, Peru
AU - Visser, Molly C.
AU - Ownby, Dennis Randall
AU - Aguilar-Villalobos, Manuel
AU - Needham, Larry L.
AU - Naeher, Luke P.
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Objective: This November 2003 pilot study investigates the correlation between serum IgE and residential endotoxin levels from a group of 18 pregnant women living in Trujillo, Peru, and investigates the impact of the demographic and lifestyle factors of this group on the IgE and endotoxin levels measured. Methods: Serum samples were collected from 19 subjects and analyzed for IgE. Dust samples were collected from the mattresses of 18 subjects and measured for endotoxin levels. A questionnaire was used to obtain demographic, socioeconomic, and lifestyle information for each subject. Results: Geometric means for IgE and endotoxin were 246.8 (GSD = 4.3, n = 19) IU/mL and 66.5 EU/mg (GSD = 1.7, n = 18), respectively. Log-transformed IgE and endotoxin were not correlated (R2 = 0.02; p = 0.60). Conclusions: Residential endotoxin and serum IgE were not correlated in this group. Potential selection bias and sample size are major limitations of the study. However, 74% (14/19) of the subjects in this study had an IgE over 100 IU/mL, a level generally considered elevated.
AB - Objective: This November 2003 pilot study investigates the correlation between serum IgE and residential endotoxin levels from a group of 18 pregnant women living in Trujillo, Peru, and investigates the impact of the demographic and lifestyle factors of this group on the IgE and endotoxin levels measured. Methods: Serum samples were collected from 19 subjects and analyzed for IgE. Dust samples were collected from the mattresses of 18 subjects and measured for endotoxin levels. A questionnaire was used to obtain demographic, socioeconomic, and lifestyle information for each subject. Results: Geometric means for IgE and endotoxin were 246.8 (GSD = 4.3, n = 19) IU/mL and 66.5 EU/mg (GSD = 1.7, n = 18), respectively. Log-transformed IgE and endotoxin were not correlated (R2 = 0.02; p = 0.60). Conclusions: Residential endotoxin and serum IgE were not correlated in this group. Potential selection bias and sample size are major limitations of the study. However, 74% (14/19) of the subjects in this study had an IgE over 100 IU/mL, a level generally considered elevated.
KW - Developing world
KW - Endotoxin
KW - IgE
KW - Peru
KW - Pregnant women
UR - http://www.scopus.com/inward/record.url?scp=33845627371&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33845627371&partnerID=8YFLogxK
U2 - 10.1016/j.envint.2006.08.009
DO - 10.1016/j.envint.2006.08.009
M3 - Article
C2 - 17011622
AN - SCOPUS:33845627371
VL - 33
SP - 147
EP - 150
JO - Environmental International
JF - Environmental International
SN - 0160-4120
IS - 2
ER -