A somatic cell hybrid mapping panel for regional assignment of human chromosome 13 DNA sequences

John K. Cowell, C. D. Mitchell

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

We have constructed somatic cell hybrids containing different overlapping deletions involving human chromosome 13. Cytogenetic characterisation of the breakpoints allowed division of the chromosome into six distinct regions. Molecular characterisation of these hybrids allowed regional assignment of anonymous DNA sequences. cDNAs. and isoenzyme variants and these hybrids should prove valuable in the analysis and isolation of genes and disease loci on chromosome 13.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalCytogenetic and Genome Research
Volume52
Issue number1-2
DOIs
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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