A somatic cell hybrid mapping panel for regional assignment of human chromosome 13 DNA sequences

John Kenneth Cowell, C. D. Mitchell

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We have constructed somatic cell hybrids containing different overlapping deletions involving human chromosome 13. Cytogenetic characterisation of the breakpoints allowed division of the chromosome into six distinct regions. Molecular characterisation of these hybrids allowed regional assignment of anonymous DNA sequences. cDNAs. and isoenzyme variants and these hybrids should prove valuable in the analysis and isolation of genes and disease loci on chromosome 13.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalCytogenetic and Genome Research
Volume52
Issue number1-2
DOIs
StatePublished - Jan 1 1989
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 13
Hybrid Cells
Human Chromosomes
Cytogenetics
Isoenzymes
Complementary DNA
Chromosomes
Genes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

Cite this

A somatic cell hybrid mapping panel for regional assignment of human chromosome 13 DNA sequences. / Cowell, John Kenneth; Mitchell, C. D.

In: Cytogenetic and Genome Research, Vol. 52, No. 1-2, 01.01.1989, p. 1-6.

Research output: Contribution to journalArticle

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