A standardized method to measure brain shifts with decompressive hemicraniectomy

Askiel Bruno, Abdurrehman Zahran, Nina Paletta, Laith Maali, Fenwick T Nichols, Ramon E Figueroa Ortiz

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background A standardized, reliable, and practical method for measuring decompressive hemicraniectomy (DHC) defects and brain shifts in malignant middle cerebral artery (MCA) territory infarction is needed for reliable comparisons between computed tomography (CT) scans. Such a method could facilitate further studies on the effects of DHC. New method We describe and apply a method for measuring DHC defects and brain shifts on CT scans in 25 patients with malignant MCA territory infarction. Craniectomy area is adjusted for variations in head size, CT slice orientation is standardized, and the site of each measurement is defined. This method uses standard radiology platforms and volume-acquired helical CT scans. Results The measurements include a DHC size index (adjusted for variations in head size), midline brain shift (subfalcine), outward brain herniation (transcalvarial), and the diameter of the contralateral atrium of the lateral ventricle. Inter-rater agreement for these measurements in a sample of 15 subjects is excellent (correlation coefficients 0.90–0.98). Comparison with existing methods In contrast to previously reported methods, this method is tested in acute stroke patients, compensates for variability in head size, and includes a midline brain shift (subfalcine) and brain ventricular system measurements. Conclusions A practical method for measuring DHC size and brain shifts designed to be consistent between scans is proposed. This method should facilitate comparisons of measurements between serial scans, between patients, and perhaps between studies. This method could be useful in medical and surgical studies of brain herniations in malignant MCA territory infarction, and possibly other conditions.

Original languageEnglish (US)
Pages (from-to)11-15
Number of pages5
JournalJournal of Neuroscience Methods
Volume280
DOIs
StatePublished - Mar 15 2017

Fingerprint

Brain
Middle Cerebral Artery Infarction
Head
Tomography
Spiral Computed Tomography
Lateral Ventricles
Radiology
Stroke

Keywords

  • Brain herniation
  • Hemicraniectomy
  • Ischemic brain edema
  • Ischemic stroke

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

A standardized method to measure brain shifts with decompressive hemicraniectomy. / Bruno, Askiel; Zahran, Abdurrehman; Paletta, Nina; Maali, Laith; Nichols, Fenwick T; Figueroa Ortiz, Ramon E.

In: Journal of Neuroscience Methods, Vol. 280, 15.03.2017, p. 11-15.

Research output: Contribution to journalArticle

@article{86bd273095404435ae38c7b32c104633,
title = "A standardized method to measure brain shifts with decompressive hemicraniectomy",
abstract = "Background A standardized, reliable, and practical method for measuring decompressive hemicraniectomy (DHC) defects and brain shifts in malignant middle cerebral artery (MCA) territory infarction is needed for reliable comparisons between computed tomography (CT) scans. Such a method could facilitate further studies on the effects of DHC. New method We describe and apply a method for measuring DHC defects and brain shifts on CT scans in 25 patients with malignant MCA territory infarction. Craniectomy area is adjusted for variations in head size, CT slice orientation is standardized, and the site of each measurement is defined. This method uses standard radiology platforms and volume-acquired helical CT scans. Results The measurements include a DHC size index (adjusted for variations in head size), midline brain shift (subfalcine), outward brain herniation (transcalvarial), and the diameter of the contralateral atrium of the lateral ventricle. Inter-rater agreement for these measurements in a sample of 15 subjects is excellent (correlation coefficients 0.90–0.98). Comparison with existing methods In contrast to previously reported methods, this method is tested in acute stroke patients, compensates for variability in head size, and includes a midline brain shift (subfalcine) and brain ventricular system measurements. Conclusions A practical method for measuring DHC size and brain shifts designed to be consistent between scans is proposed. This method should facilitate comparisons of measurements between serial scans, between patients, and perhaps between studies. This method could be useful in medical and surgical studies of brain herniations in malignant MCA territory infarction, and possibly other conditions.",
keywords = "Brain herniation, Hemicraniectomy, Ischemic brain edema, Ischemic stroke",
author = "Askiel Bruno and Abdurrehman Zahran and Nina Paletta and Laith Maali and Nichols, {Fenwick T} and {Figueroa Ortiz}, {Ramon E}",
year = "2017",
month = "3",
day = "15",
doi = "10.1016/j.jneumeth.2017.01.021",
language = "English (US)",
volume = "280",
pages = "11--15",
journal = "Journal of Neuroscience Methods",
issn = "0165-0270",
publisher = "Elsevier",

}

TY - JOUR

T1 - A standardized method to measure brain shifts with decompressive hemicraniectomy

AU - Bruno, Askiel

AU - Zahran, Abdurrehman

AU - Paletta, Nina

AU - Maali, Laith

AU - Nichols, Fenwick T

AU - Figueroa Ortiz, Ramon E

PY - 2017/3/15

Y1 - 2017/3/15

N2 - Background A standardized, reliable, and practical method for measuring decompressive hemicraniectomy (DHC) defects and brain shifts in malignant middle cerebral artery (MCA) territory infarction is needed for reliable comparisons between computed tomography (CT) scans. Such a method could facilitate further studies on the effects of DHC. New method We describe and apply a method for measuring DHC defects and brain shifts on CT scans in 25 patients with malignant MCA territory infarction. Craniectomy area is adjusted for variations in head size, CT slice orientation is standardized, and the site of each measurement is defined. This method uses standard radiology platforms and volume-acquired helical CT scans. Results The measurements include a DHC size index (adjusted for variations in head size), midline brain shift (subfalcine), outward brain herniation (transcalvarial), and the diameter of the contralateral atrium of the lateral ventricle. Inter-rater agreement for these measurements in a sample of 15 subjects is excellent (correlation coefficients 0.90–0.98). Comparison with existing methods In contrast to previously reported methods, this method is tested in acute stroke patients, compensates for variability in head size, and includes a midline brain shift (subfalcine) and brain ventricular system measurements. Conclusions A practical method for measuring DHC size and brain shifts designed to be consistent between scans is proposed. This method should facilitate comparisons of measurements between serial scans, between patients, and perhaps between studies. This method could be useful in medical and surgical studies of brain herniations in malignant MCA territory infarction, and possibly other conditions.

AB - Background A standardized, reliable, and practical method for measuring decompressive hemicraniectomy (DHC) defects and brain shifts in malignant middle cerebral artery (MCA) territory infarction is needed for reliable comparisons between computed tomography (CT) scans. Such a method could facilitate further studies on the effects of DHC. New method We describe and apply a method for measuring DHC defects and brain shifts on CT scans in 25 patients with malignant MCA territory infarction. Craniectomy area is adjusted for variations in head size, CT slice orientation is standardized, and the site of each measurement is defined. This method uses standard radiology platforms and volume-acquired helical CT scans. Results The measurements include a DHC size index (adjusted for variations in head size), midline brain shift (subfalcine), outward brain herniation (transcalvarial), and the diameter of the contralateral atrium of the lateral ventricle. Inter-rater agreement for these measurements in a sample of 15 subjects is excellent (correlation coefficients 0.90–0.98). Comparison with existing methods In contrast to previously reported methods, this method is tested in acute stroke patients, compensates for variability in head size, and includes a midline brain shift (subfalcine) and brain ventricular system measurements. Conclusions A practical method for measuring DHC size and brain shifts designed to be consistent between scans is proposed. This method should facilitate comparisons of measurements between serial scans, between patients, and perhaps between studies. This method could be useful in medical and surgical studies of brain herniations in malignant MCA territory infarction, and possibly other conditions.

KW - Brain herniation

KW - Hemicraniectomy

KW - Ischemic brain edema

KW - Ischemic stroke

UR - http://www.scopus.com/inward/record.url?scp=85011818881&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85011818881&partnerID=8YFLogxK

U2 - 10.1016/j.jneumeth.2017.01.021

DO - 10.1016/j.jneumeth.2017.01.021

M3 - Article

C2 - 28163065

AN - SCOPUS:85011818881

VL - 280

SP - 11

EP - 15

JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

SN - 0165-0270

ER -