Abstract
Forty-five patients with recurrent renal stone were examined for distal renal tubular acidosis (dRTA) defects by acid challenge test (150 mg ammonium chloride/kg body weight). Their 24-h urine samples were analysed for creatinine, calcium, oxalic acid, inorganic phosphorus, uric acid, magnesium and citric acid. One-hour urine samples before acid load and hourly samples for the 7 h following acid challenge test were collected and analysed for creatinine, calcium, citric acid, inorganic phosphorus, titratable acidity, and ammonium. The incidence of distal RTA defect was 22.2% in the patients examined. The major biochemical characteristics in RTA patients compared with patients without RTA were: (a) significantly higher urinary pH, (b) significantly lower excretion of citric acid, (c) no significant difference in calcium excretion and (d) a tendency toward lower titratable acidity and ammonium excretion.
Original language | English (US) |
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Pages (from-to) | 201-3 |
Number of pages | 3 |
Journal | Urological Research |
Volume | 23 |
Issue number | 3 |
State | Published - 1995 |
Keywords
- Acidosis, Renal Tubular
- Adult
- Citrates
- Citric Acid
- Female
- Humans
- Hydrogen-Ion Concentration
- Kidney Calculi
- Kidney Tubules, Distal
- Male
- Middle Aged
- Recurrence
- Urine