A three-dimensional morphometric study of craniofacial shape in schizophrenia

Peter F. Buckley, David Dean, Fred L. Bookstein, Seungho Han, Michael Yerukhimovich, Kyoung June Min, Beth Singer

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Background: Subtle dysmorphogenesis of the craniofacial region constitutes important corroborating evidence of the neurodevelopmental origins of schizophrenia. Advances in facial visualization now allow for three-dimensional anthropometric evaluations of potentially greater discriminatory power in examining the complex geometric relationships of facial topography. Method: Sixty-five anthropometrically derived landmarks were identified from three-dimensional facial images collected from 14 patients with schizophrenia and 11 comparison subjects, imaged with a high-resolution, portable laser scanner. Results: Using the Procrustes morphometric approach for shape analysis, the difference in mean shapes was highly significant, with patients exhibiting superoinferior elongation of the face. Conclusions: The topography of craniofacial anomalies in schizophrenia is not random and points to midline deformation.

Original languageEnglish (US)
Pages (from-to)606-608
Number of pages3
JournalAmerican Journal of Psychiatry
Volume162
Issue number3
DOIs
StatePublished - Mar 1 2005

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Schizophrenia
Three-Dimensional Imaging
Lasers
Power (Psychology)

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Buckley, P. F., Dean, D., Bookstein, F. L., Han, S., Yerukhimovich, M., Min, K. J., & Singer, B. (2005). A three-dimensional morphometric study of craniofacial shape in schizophrenia. American Journal of Psychiatry, 162(3), 606-608. https://doi.org/10.1176/appi.ajp.162.3.606

A three-dimensional morphometric study of craniofacial shape in schizophrenia. / Buckley, Peter F.; Dean, David; Bookstein, Fred L.; Han, Seungho; Yerukhimovich, Michael; Min, Kyoung June; Singer, Beth.

In: American Journal of Psychiatry, Vol. 162, No. 3, 01.03.2005, p. 606-608.

Research output: Contribution to journalArticle

Buckley, PF, Dean, D, Bookstein, FL, Han, S, Yerukhimovich, M, Min, KJ & Singer, B 2005, 'A three-dimensional morphometric study of craniofacial shape in schizophrenia', American Journal of Psychiatry, vol. 162, no. 3, pp. 606-608. https://doi.org/10.1176/appi.ajp.162.3.606
Buckley PF, Dean D, Bookstein FL, Han S, Yerukhimovich M, Min KJ et al. A three-dimensional morphometric study of craniofacial shape in schizophrenia. American Journal of Psychiatry. 2005 Mar 1;162(3):606-608. https://doi.org/10.1176/appi.ajp.162.3.606
Buckley, Peter F. ; Dean, David ; Bookstein, Fred L. ; Han, Seungho ; Yerukhimovich, Michael ; Min, Kyoung June ; Singer, Beth. / A three-dimensional morphometric study of craniofacial shape in schizophrenia. In: American Journal of Psychiatry. 2005 ; Vol. 162, No. 3. pp. 606-608.
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