@article{3d6ff754680a49d4a72e6abe8e1cff08,
title = "A transcription map of the major histocompatibility complex (MHC) class I region",
abstract = "We have applied cDNA hybridization selection to nine YACs spanning 3 Mb of genomic DNA from a region centromeric to HLA-A to the histone cluster that lies telomeric to the human major histocompatibility complex (MHC). In addition to Class I genes and pseudogenes, we describe over 63 genes and 23 additional expressed sequence tags distributed throughout the region. Many of the full-length genes belong to gene families. Prominent among these are a group of genes encoding proteins showing homology to the carboxylterminal sequences of butyrophilin and an additional group of zinc finger genes. We also detected several previously undefined genes that are specifically expressed in cells of the immune system, indicating a more complex role of the MHC in the immune response than has been appreciated.",
author = "Gruen, {J. R.} and Nalabolu, {S. R.} and Chu, {T. W.} and C. Bowlus and Fan, {W. F.} and Goei, {Vita Lan-Ing} and H. Wei and R. Sivakamasundari and Liu, {Y. C.} and Xu, {H. X.} and S. Parimoo and G. Nallur and R. Ajioka and H. Shukla and P. Bray-Ward and J. Pan and Weissman, {S. M.}",
note = "Funding Information: The authors thank D. Le Paslier (CEPH) for supplying YAC clones, H. Zoghbi (Baylor) for R66, T. ZhenLi (Markey Trust/BCMM Sequencing Core) for sequencing, L. Infeld-Stone and C. Erikson (Yale Biomedical Computing Center) for computer support, A. J. Bhargava for the Jurkat cDNA library, D. Camputaro for manuscript preparation, and S. K. Hendren for editorial comments and background. This work was supported in part by NIH 1R29DK45819-03 (J.R.G.), March of Dimes 6-FY95-0050 (J.R.G.), Lucille P. Markey Charitable Trust (J.R.G.), NIH Outstanding Investigator Grant CA42556-10 (S.M.W.), NIH DK02303-01 (T.W.C.), NIH HD07388-01 (V.L.G.), NIH HG00272 (P.B.-W.), and NIH DK-20630 (R.A.).",
year = "1996",
month = aug,
day = "15",
doi = "10.1006/geno.1996.0427",
language = "English (US)",
volume = "36",
pages = "70--85",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "1",
}