Accessing the vocal folds by transcutaneous injection

William Gordon Pearson, Christoph T. Hutchinson, J. Pieter Noordzij

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This study tested three techniques and two approaches to access the vocal fold (VF) by transcutaneous injection using a cadaver model. The three techniques include an anatomically informed geometric technique, flexible laryngoscope (FL) guidance, and planned injection with use of computed tomography (CT). The two approaches for injection include the thyrohyoid membrane (THM) and the cricothyroid membrane (CTM). The hypothesis was that the VF is more reliably reached with techniques using technological visualization and the THM and CTM provides equal access to the VF. A geometric approach to the VF was developed and tested on seven formalin-fixed human cadavers with three injections of 0.5 ml pigmented acrylic polymer through the CTM and one through the THM. The FL-guided technique through the THM and the CTM was tested on eight formalin-fixed human cadavers and the CT informed technique on two subjects. All tests were inspected by dissection and results recorded. Pertinent measurements and characteristics of each technique were recorded. Data were analyzed for statistical significance for each approach and technique. A chi-square analysis revealed that a technology guided technique was more successful than anatomical knowledge alone (X2 = 6.55, P = 0.01). The null hypothesis that the VF was equally accessed through the THM and the CTM was rejected (X2 = 5.33, P = 0.02). We found that technology guided visualization is better than anatomical knowledge alone in accessing the VF. We also found that the CTM approach provides more reliable access to the entire length of the VF.

Original languageEnglish (US)
Pages (from-to)270-276
Number of pages7
JournalClinical Anatomy
Volume23
Issue number3
DOIs
StatePublished - Apr 1 2010

Fingerprint

Vocal Cords
Injections
Membranes
Cadaver
Laryngoscopes
Formaldehyde
Tomography
Technology
Dissection
Polymers

Keywords

  • Injection
  • Laryngoplasty
  • Vocal fold

ASJC Scopus subject areas

  • Anatomy
  • Histology

Cite this

Pearson, W. G., Hutchinson, C. T., & Noordzij, J. P. (2010). Accessing the vocal folds by transcutaneous injection. Clinical Anatomy, 23(3), 270-276. https://doi.org/10.1002/ca.20920

Accessing the vocal folds by transcutaneous injection. / Pearson, William Gordon; Hutchinson, Christoph T.; Noordzij, J. Pieter.

In: Clinical Anatomy, Vol. 23, No. 3, 01.04.2010, p. 270-276.

Research output: Contribution to journalArticle

Pearson, WG, Hutchinson, CT & Noordzij, JP 2010, 'Accessing the vocal folds by transcutaneous injection', Clinical Anatomy, vol. 23, no. 3, pp. 270-276. https://doi.org/10.1002/ca.20920
Pearson WG, Hutchinson CT, Noordzij JP. Accessing the vocal folds by transcutaneous injection. Clinical Anatomy. 2010 Apr 1;23(3):270-276. https://doi.org/10.1002/ca.20920
Pearson, William Gordon ; Hutchinson, Christoph T. ; Noordzij, J. Pieter. / Accessing the vocal folds by transcutaneous injection. In: Clinical Anatomy. 2010 ; Vol. 23, No. 3. pp. 270-276.
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