Accurate measurements of oxygen saturation in neonates

Paired arterial and venous blood analyses

Shyang-Yun Pamela Shiao

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: The aim of this study was to examine the accuracy of arterial oxygen saturation (SaO 2 ) and venous oxygen saturation (SvO 2 ) with paired arterial and venous (AV) blood in relation to pulse oximetry saturation (SpO 2 ) and oxyhemoglobin (HbO 2 ) with fetal hemoglobin determination, and their HbO 2 dissociation curves. Method: Twelve preterm neonates with gestational ages ranging from 27 to 34 weeks at birth, who had umbilical AV lines inserted, were investigated. Analyses were performed with 37 pairs of AV blood samples by using a blood volume safety protocol. Results: The mean differences between SaO 2 and SvO 2 , and AV HbO 2 were both 6 percent (±6.9 and ±6.7 percent, respectively), with higher SvO 2 than those reported for adults. Biases were 2.1 ± 0.49 for SaO 2 , 2.0 ± 0.44 for SvO 2 , and 3.1 ± 0.45 for SpO 2 , compared against HbO 2 . With left-shifted HbO 2 dissociation curves in neonates, for the critical values of oxygen tension values between 50 and 75 millimeters of mercury, HbO 2 ranged from 92 to 93.4 percent; SaO 2 ranged from 94.5 to 95.7 percent; and SpO 2 ranged from 93.7 to 96.3 percent (compared to 85-94 percent in healthy adults). Conclusions: In neonates, both left-shifted HbO 2 dissociation curve and lower AV differences of oxygen saturation measurements indicated low flow of oxygen to the body tissues. These findings demonstrate the importance of accurate assessment of oxygenation statues in neonates.

Original languageEnglish (US)
Pages (from-to)170-178
Number of pages9
JournalNewborn and Infant Nursing Reviews
Volume5
Issue number4
DOIs
StatePublished - Dec 1 2005

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Newborn Infant
Oxygen
Blood Safety
Umbilicus
Fetal Hemoglobin
Vascular Access Devices
Oxyhemoglobins
Oximetry
Blood Volume
Mercury
Gestational Age
Parturition

ASJC Scopus subject areas

  • Pediatrics

Cite this

Accurate measurements of oxygen saturation in neonates : Paired arterial and venous blood analyses. / Shiao, Shyang-Yun Pamela.

In: Newborn and Infant Nursing Reviews, Vol. 5, No. 4, 01.12.2005, p. 170-178.

Research output: Contribution to journalArticle

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