Abstract
We have determined action spectra for transformation of human embryonic skin and muscle fibroblasts to anchorage-independent growth. Tests under our experimental conditions indicate that reciprocity holds for photon rate and exposure time and that all the dose-effect curves in the wavelength range of 248 to 297 nm are similar. These data can be used to construct action spectra with a maximum at about 265 nm, which do not implicate moieties other than nucleic acids as absorbers in the transformation process.
Original language | English (US) |
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Pages (from-to) | 2211-2214 |
Number of pages | 4 |
Journal | Cancer Research |
Volume | 41 |
Issue number | 6 |
State | Published - Jun 1 1981 |
Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cancer Research