TY - JOUR
T1 - Adenosquamous carcinoma
T2 - A case report with immunohistochemical evaluation
AU - Abdelsayed, Rafik A.
AU - Sangueza, Omar P.
AU - Newhouse, Ricney F.
AU - Singh, Baldev S.
PY - 1998
Y1 - 1998
N2 - The histogenetic origin of adenosquamous carcinoma, a high-grade variant of malignant epithelial neoplasm, has long been debated. We report a case that clearly demonstrated a mucosal surface epithelial origin. This concept was supported through histologic analysis of hematoxylin- and eosin-stained sections, as well as by the pattern of immunohistochemical reactivity with antibodies directed against low and high molecular weight cytokeratins, cell adhesion molecules (CAM 5.2), and carcinoembryonic antigens. The histologic differential diagnosis, biological behavior, and prognosis of adenosquamous carcinoma are also examined.
AB - The histogenetic origin of adenosquamous carcinoma, a high-grade variant of malignant epithelial neoplasm, has long been debated. We report a case that clearly demonstrated a mucosal surface epithelial origin. This concept was supported through histologic analysis of hematoxylin- and eosin-stained sections, as well as by the pattern of immunohistochemical reactivity with antibodies directed against low and high molecular weight cytokeratins, cell adhesion molecules (CAM 5.2), and carcinoembryonic antigens. The histologic differential diagnosis, biological behavior, and prognosis of adenosquamous carcinoma are also examined.
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U2 - 10.1016/S1079-2104(98)90422-X
DO - 10.1016/S1079-2104(98)90422-X
M3 - Article
C2 - 9503452
AN - SCOPUS:0032219457
SN - 1079-2104
VL - 85
SP - 173
EP - 177
JO - Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
JF - Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
IS - 2
ER -