Admission prediction of expected final myocardial infarct size using weighted ST-segment, Q wave, and T wave measurements

Research output: Contribution to journalArticle

Abstract

Formulas for predicting final acute myocardial infarction (MI) size from ST-segment deviation on an initial electrocardiogram were proposed by Aldrich et al. for anterior and inferior infarct locations. This study of 529 patients who did not receive thrombolytic therapy was performed to determine the effectiveness of the Aldrich formulas for predicting final QRS MI size; to propose new formulas for predicting final MI size using ST-segment deviation, Q wave, and T wave information in a development population of 322 patients; and to evaluate the new formulas in a randomly selected population of 207 patients. The Aldrich formulas achieved correlations with final infarct size of r = .40 for anterior and r = .43 for inferior MI locations in the present population which are weaker than those previously reported. Formulas that consider electrocardiographic parameters in addition to ST- segment deviation were proposed for both anterior and and inferior final MI size. In the test set of 207 patients, these, models explained 16.9% and 15.2% of the variation in final MI size for anterior and interior locations respectively. They may prove useful in assessing the extent of myocardial salvage where interventions are to be tested.

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Myocardial Infarction
Inferior Wall Myocardial Infarction
Population
Thrombolytic Therapy
Electrocardiography

Keywords

  • ECG parameters
  • infarct size
  • myocardial infarction
  • ST-segment deviation
  • stepwise linear recognition

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Wilkins, M. L., Maynard, C., Annex, B. H., Clemmensen, P., Elias, W. J., Gibson, R. S., ... Wagner, G. S. (1997). Admission prediction of expected final myocardial infarct size using weighted ST-segment, Q wave, and T wave measurements. Journal of Electrocardiology, 30(1), 1-7. https://doi.org/10.1016/S0022-0736(97)80029-5

Admission prediction of expected final myocardial infarct size using weighted ST-segment, Q wave, and T wave measurements. / Wilkins, Michelle L.; Maynard, Charles; Annex, Brian H.; Clemmensen, Peter; Elias, William J.; Gibson, Robert S.; Lee, Kerry L.; Pryor, Aurora D.; Selker, Harry; Turner, John; Weaver, W. Douglas; Anderson, Stanley T.; Wagner, Galen S.

In: Journal of Electrocardiology, Vol. 30, No. 1, 01.01.1997, p. 1-7.

Research output: Contribution to journalArticle

Wilkins, ML, Maynard, C, Annex, BH, Clemmensen, P, Elias, WJ, Gibson, RS, Lee, KL, Pryor, AD, Selker, H, Turner, J, Weaver, WD, Anderson, ST & Wagner, GS 1997, 'Admission prediction of expected final myocardial infarct size using weighted ST-segment, Q wave, and T wave measurements', Journal of Electrocardiology, vol. 30, no. 1, pp. 1-7. https://doi.org/10.1016/S0022-0736(97)80029-5
Wilkins, Michelle L. ; Maynard, Charles ; Annex, Brian H. ; Clemmensen, Peter ; Elias, William J. ; Gibson, Robert S. ; Lee, Kerry L. ; Pryor, Aurora D. ; Selker, Harry ; Turner, John ; Weaver, W. Douglas ; Anderson, Stanley T. ; Wagner, Galen S. / Admission prediction of expected final myocardial infarct size using weighted ST-segment, Q wave, and T wave measurements. In: Journal of Electrocardiology. 1997 ; Vol. 30, No. 1. pp. 1-7.
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