Adopting the principles of collagen biomineralization for intrafibrillar infiltration of yttria-stabilized zirconia into three-dimensional collagen scaffolds

Bin Zhou, Li Na Niu, Wei Shi, Wei Zhang, Dwayne D. Arola, Lorenzo Breschi, Jing Mao, Ji Hua Chen, David Henry Pashley, Franklin Chi Meng Tay

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In this paper, a process for generating collagen-yttria-stabilized amorphous zirconia hybrid scaffolds by introducing acetylacetone-inhibited zirconia precursor nanodroplets into a poly(allylamine)-coated collagen matrix is reported. This polyelectrolyte coating triggers intrafibrillar condensation of the precursors into amorphous zirconia, which is subsequently transformed into yttria-stabilized zirconia after calcination. These findings represent a new paradigm in the synthesis of non-naturally occurring collagen-based hybrid scaffolds under alcoholic mineralizing conditions. Acac-stablized yttria-stabilized zirconia (YSZ) nano-sized precursors infuse into the fibril and coalesce in the presence of the PAH-crosslinked collagen molecules to form larger-sized precursor droplets. These precursor droplets further condense in the presence of water available within the intrafibrillar compartments of the collagen fibril into amorphous YSZ nanoparticles.

Original languageEnglish (US)
Pages (from-to)1895-1903
Number of pages9
JournalAdvanced Functional Materials
Volume24
Issue number13
DOIs
StatePublished - Apr 2 2014

Fingerprint

Biomineralization
Yttria stabilized zirconia
infiltration
collagens
Scaffolds (biology)
yttria-stabilized zirconia
Infiltration
Collagen
Scaffolds
zirconium oxides
Zirconia
Allylamine
acetylacetone
Yttrium oxide
polycyclic aromatic hydrocarbons
compartments
Polycyclic aromatic hydrocarbons
Polyelectrolytes
Calcination
roasting

Keywords

  • biomimetic syntheses
  • collagen
  • intrafibrillar
  • zirconia

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics

Cite this

Adopting the principles of collagen biomineralization for intrafibrillar infiltration of yttria-stabilized zirconia into three-dimensional collagen scaffolds. / Zhou, Bin; Niu, Li Na; Shi, Wei; Zhang, Wei; Arola, Dwayne D.; Breschi, Lorenzo; Mao, Jing; Chen, Ji Hua; Pashley, David Henry; Tay, Franklin Chi Meng.

In: Advanced Functional Materials, Vol. 24, No. 13, 02.04.2014, p. 1895-1903.

Research output: Contribution to journalArticle

Zhou, Bin ; Niu, Li Na ; Shi, Wei ; Zhang, Wei ; Arola, Dwayne D. ; Breschi, Lorenzo ; Mao, Jing ; Chen, Ji Hua ; Pashley, David Henry ; Tay, Franklin Chi Meng. / Adopting the principles of collagen biomineralization for intrafibrillar infiltration of yttria-stabilized zirconia into three-dimensional collagen scaffolds. In: Advanced Functional Materials. 2014 ; Vol. 24, No. 13. pp. 1895-1903.
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