Adrenal medulla gangliosides. A comparative study of some mammals

Howard C. Price, Robert K Yu

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

1. 1. Gangliosides were isolated from the adrenal medulla of man, horse, ox, sheep and swine. 2. 2. Yields of ganglioside-bound sialic acids were found by GLC analysis to be approx 150 μg/g fresh tissue for all species studied. 3. 3. The distribution between the two common sialic acids, N-acetylneuraminic acid (NANA) and N-glycolylneuraminic acid (NGNA) varied considerably. For porcine and bovine mixtures NGNA accounted for approx 60% of ganglioside-bound sialic acids, whereas no NGNA was detected in the human mixture. 4. 4. The thin layer chromatogram of the bovine mixture shows a predominance of hematosides over slower-migrating "brain-type" gangliosides. In the porcine mixture, however, slower-migrating gangliosides predominate.

Original languageEnglish (US)
Pages (from-to)451-454
Number of pages4
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume54
Issue number4
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

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Adrenal Medulla
Mammals
Gangliosides
Sialic Acids
Swine
G(M3) Ganglioside
N-Acetylneuraminic Acid
Horses
Brain
Sheep
Tissue
N-glycolylneuraminic acid

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology

Cite this

Adrenal medulla gangliosides. A comparative study of some mammals. / Price, Howard C.; Yu, Robert K.

In: Comparative Biochemistry and Physiology -- Part B: Biochemistry and, Vol. 54, No. 4, 01.01.1976, p. 451-454.

Research output: Contribution to journalArticle

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