TY - JOUR
T1 - Adrenal medulla gangliosides. A comparative study of some mammals
AU - Price, Howard C.
AU - Yu, Robert K.
N1 - Funding Information:
This work was supported in part by research grants from the Graduate School of Marshall University (to HCP) and Grant 1 ROI NS 11853 from the National Institute of Health, U.S. Public Health Service (to RKY~
PY - 1976
Y1 - 1976
N2 - 1. 1. Gangliosides were isolated from the adrenal medulla of man, horse, ox, sheep and swine. 2. 2. Yields of ganglioside-bound sialic acids were found by GLC analysis to be approx 150 μg/g fresh tissue for all species studied. 3. 3. The distribution between the two common sialic acids, N-acetylneuraminic acid (NANA) and N-glycolylneuraminic acid (NGNA) varied considerably. For porcine and bovine mixtures NGNA accounted for approx 60% of ganglioside-bound sialic acids, whereas no NGNA was detected in the human mixture. 4. 4. The thin layer chromatogram of the bovine mixture shows a predominance of hematosides over slower-migrating "brain-type" gangliosides. In the porcine mixture, however, slower-migrating gangliosides predominate.
AB - 1. 1. Gangliosides were isolated from the adrenal medulla of man, horse, ox, sheep and swine. 2. 2. Yields of ganglioside-bound sialic acids were found by GLC analysis to be approx 150 μg/g fresh tissue for all species studied. 3. 3. The distribution between the two common sialic acids, N-acetylneuraminic acid (NANA) and N-glycolylneuraminic acid (NGNA) varied considerably. For porcine and bovine mixtures NGNA accounted for approx 60% of ganglioside-bound sialic acids, whereas no NGNA was detected in the human mixture. 4. 4. The thin layer chromatogram of the bovine mixture shows a predominance of hematosides over slower-migrating "brain-type" gangliosides. In the porcine mixture, however, slower-migrating gangliosides predominate.
UR - http://www.scopus.com/inward/record.url?scp=0017062323&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017062323&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(76)90120-6
DO - 10.1016/0305-0491(76)90120-6
M3 - Article
C2 - 939085
AN - SCOPUS:0017062323
SN - 0305-0491
VL - 54
SP - 451
EP - 454
JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
IS - 4
ER -