1. 1. Gangliosides were isolated from the adrenal medulla of man, horse, ox, sheep and swine. 2. 2. Yields of ganglioside-bound sialic acids were found by GLC analysis to be approx 150 μg/g fresh tissue for all species studied. 3. 3. The distribution between the two common sialic acids, N-acetylneuraminic acid (NANA) and N-glycolylneuraminic acid (NGNA) varied considerably. For porcine and bovine mixtures NGNA accounted for approx 60% of ganglioside-bound sialic acids, whereas no NGNA was detected in the human mixture. 4. 4. The thin layer chromatogram of the bovine mixture shows a predominance of hematosides over slower-migrating "brain-type" gangliosides. In the porcine mixture, however, slower-migrating gangliosides predominate.
|Original language||English (US)|
|Number of pages||4|
|Journal||Comparative Biochemistry and Physiology -- Part B: Biochemistry and|
|State||Published - 1976|
ASJC Scopus subject areas
- Molecular Biology