Adrenal medulla gangliosides. A comparative study of some mammals

Howard C. Price, Robert K. Yu

Research output: Contribution to journalArticle

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Abstract

1. 1. Gangliosides were isolated from the adrenal medulla of man, horse, ox, sheep and swine. 2. 2. Yields of ganglioside-bound sialic acids were found by GLC analysis to be approx 150 μg/g fresh tissue for all species studied. 3. 3. The distribution between the two common sialic acids, N-acetylneuraminic acid (NANA) and N-glycolylneuraminic acid (NGNA) varied considerably. For porcine and bovine mixtures NGNA accounted for approx 60% of ganglioside-bound sialic acids, whereas no NGNA was detected in the human mixture. 4. 4. The thin layer chromatogram of the bovine mixture shows a predominance of hematosides over slower-migrating "brain-type" gangliosides. In the porcine mixture, however, slower-migrating gangliosides predominate.

Original languageEnglish (US)
Pages (from-to)451-454
Number of pages4
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume54
Issue number4
DOIs
Publication statusPublished - 1976
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology

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