Advances in image-guided intratumoral drug delivery techniques

Luis Solorio, Ravi B. Patel, Hanping Wu, Tianyi Krupka, Agata A. Exner

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Image-guided drug delivery provides a means for treating a variety of diseases with minimal systemic involvement while concurrently monitoring treatment efficacy. These therapies are particularly useful to the field of interventional oncology, where elevation of tumor drug levels, reduction of systemic side effects and post-therapy assessment are essential. This review highlights three such image-guided procedures: transarterial chemoembolization, drug-eluting implants and convection-enhanced delivery. Advancements in medical imaging technology have resulted in a growing number of new applications, including image-guided drug delivery. This minimally invasive approach provides a comprehensive answer to many challenges with local drug delivery. Future evolution of imaging devices, image-acquisition techniques and multifunctional delivery agents will lead to a paradigm shift in patient care.

Original languageEnglish (US)
Pages (from-to)307-322
Number of pages16
JournalTherapeutic Delivery
Volume1
Issue number2
DOIs
StatePublished - Aug 2010
Externally publishedYes

ASJC Scopus subject areas

  • Pharmaceutical Science

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