Adverse obstetric outcomes associated with sonographically identified large uterine fibroids

Valerie I. Shavell, Mili Thakur, Anjali Sawant, Michael L. Kruger, Theodore B. Jones, Manvinder Singh, Elizabeth E. Puscheck, Michael Peter Diamond

Research output: Contribution to journalArticle

71 Scopus citations

Abstract

Study Objective: To determine the impact of sonographically identified large uterine fibroids (>5 cm in diameter) on obstetric outcomes. Design: Retrospective cohort study. Setting: University teaching hospital. Patient(s): Women with singleton gestations (n = 95) noted to have uterine fibroids on obstetric ultrasonography from September 2009 through April 2010 and age-matched controls (n = 95). Intervention(s): None. Main Outcome Measure(s): Obstetric outcomes including short cervix, preterm premature rupture of membranes, and preterm delivery. Result(s): Compared to women with no fibroids or small fibroids (≤5 cm), women with large fibroids (>5 cm) delivered at a significantly earlier gestational age (38.6 vs. 38.4 vs. 36.5 weeks). Short cervix, preterm premature rupture of membranes, and preterm delivery were also significantly more frequent in the large fibroid group, and were associated with number of fibroids >5 cm in diameter. Blood loss at delivery was significantly higher in the large fibroid group (486.8 vs. 535.6 vs. 645.1 mL), as was need for postpartum blood transfusion (1.1 vs. 0.0 vs. 12.2%). Conclusion(s): Women with large uterine fibroids in pregnancy are at significantly increased risk for delivery at an earlier gestational age compared to women with small or no fibroids, as well as obstetric complications including excess blood loss and increased frequency of postpartum blood transfusion.

Original languageEnglish (US)
Pages (from-to)107-110
Number of pages4
JournalFertility and Sterility
Volume97
Issue number1
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

Keywords

  • blood transfusion
  • Fibroid
  • leiomyoma
  • pregnancy
  • premature rupture of membranes
  • preterm delivery
  • short cervix
  • ultrasonography

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Adverse obstetric outcomes associated with sonographically identified large uterine fibroids'. Together they form a unique fingerprint.

Cite this