Aggression and schizophrenia

Efficacy of risperidone

Peter F. Buckley, Zafar Y. Ibrahim, Beth Singer, Bruce Orr, Karl Donenwirth, Parminder S. Brar

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

The advent of novel antipsychotic medications has raised treatment expectations for patients with severe mental illness. In this regard, clozapine has been particularly effective in reducing aggressive behavior in patients with schizophrenia. This study compared the efficacy of risperidone and conventional antipsychotic medications in the management of hostile patients. Improvements in the level of aggression were evident over time in both treatment groups, and a similar response between risperidone and typical antipsychotics was observed. Future studies should address the relative role of typical antipsychotics, adjunctive agents, and novel antipsychotic medications in the pharmacological management of persistent aggression in patients with schizophrenia.

Original languageEnglish (US)
Pages (from-to)173-181
Number of pages9
JournalJournal of the American Academy of Psychiatry and the Law
Volume25
Issue number2
StatePublished - Dec 1 1997

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Risperidone
Aggression
Antipsychotic Agents
Schizophrenia
Clozapine
Pharmacology
Therapeutics

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Psychiatry and Mental health

Cite this

Buckley, P. F., Ibrahim, Z. Y., Singer, B., Orr, B., Donenwirth, K., & Brar, P. S. (1997). Aggression and schizophrenia: Efficacy of risperidone. Journal of the American Academy of Psychiatry and the Law, 25(2), 173-181.

Aggression and schizophrenia : Efficacy of risperidone. / Buckley, Peter F.; Ibrahim, Zafar Y.; Singer, Beth; Orr, Bruce; Donenwirth, Karl; Brar, Parminder S.

In: Journal of the American Academy of Psychiatry and the Law, Vol. 25, No. 2, 01.12.1997, p. 173-181.

Research output: Contribution to journalArticle

Buckley, PF, Ibrahim, ZY, Singer, B, Orr, B, Donenwirth, K & Brar, PS 1997, 'Aggression and schizophrenia: Efficacy of risperidone', Journal of the American Academy of Psychiatry and the Law, vol. 25, no. 2, pp. 173-181.
Buckley PF, Ibrahim ZY, Singer B, Orr B, Donenwirth K, Brar PS. Aggression and schizophrenia: Efficacy of risperidone. Journal of the American Academy of Psychiatry and the Law. 1997 Dec 1;25(2):173-181.
Buckley, Peter F. ; Ibrahim, Zafar Y. ; Singer, Beth ; Orr, Bruce ; Donenwirth, Karl ; Brar, Parminder S. / Aggression and schizophrenia : Efficacy of risperidone. In: Journal of the American Academy of Psychiatry and the Law. 1997 ; Vol. 25, No. 2. pp. 173-181.
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