Abstract
Although the increased incidence of common cancers with age on one hand and immunosenescence on the other are both well documented in animal models and in humans, evidence for a causal link between the two is controversial. It is, therefore, most appropriate to critically consider whether the dysfunctional immune processes occurring with aging may play a contributing role in the increased incidence of cancer with aging. Indeed whether or not immunosenescence plays a significant role could have a determinant impact on devising cancer prevention and/or immunotherapeutic strategies for the presently growing elderly population.
| Original language | English (US) |
|---|---|
| Title of host publication | Handbook on Immunosenescence |
| Subtitle of host publication | Basic Understanding and Clinical Applications |
| Publisher | Springer Netherlands |
| Pages | 1119-1138 |
| Number of pages | 20 |
| Volume | 9781402090639 |
| ISBN (Electronic) | 9781402090639 |
| ISBN (Print) | 9781402090622 |
| DOIs | |
| State | Published - 2009 |
| Externally published | Yes |
Keywords
- Adoptive immunotherapy
- Immuno-editing
- Immuno-surveillance
- Inflammation
- Primary immuno-deficiency
ASJC Scopus subject areas
- General Medicine
