ALSUntangled # 69: astaxanthin

Timothy Fullam; Carmel Armon; Paul Barkhaus; Benjamin Barnes; Morgan Beauchamp; Michael Benatar; Tulio Bertorini; Robert Bowser; Mark Bromberg; Javier Mascias Cadavid; Gregory T. Carter; Mazen Dimachkie; Dave Ennist; Eva L. Feldman; Terry Heiman-patterson; Sartaj Jhooty; Isaac Lund; Christopher Mcdermott; Gary Pattee; Dylan Ratner; Paul Wicks; Richard Bedlack

doi:10.1080/21678421.2023.2171302

ALSUntangled # 69: astaxanthin

Timothy Fullam, Carmel Armon, Paul Barkhaus, Benjamin Barnes, Morgan Beauchamp, Michael Benatar, Tulio Bertorini, Robert Bowser, Mark Bromberg, Javier Mascias Cadavid, Gregory T. Carter, Mazen Dimachkie, Dave Ennist, Eva L. Feldman, Terry Heiman-patterson, Sartaj Jhooty, Isaac Lund, Christopher Mcdermott, Gary Pattee, Dylan RatnerPaul Wicks, Richard Bedlack

Neurology

Research output: Contribution to journal › Article › peer-review

Abstract

ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review astaxanthin which has plausible mechanisms for slowing ALS progression including antioxidant, anti-inflammatory, and anti-apoptotic effects. While there are no ALS-specific pre-clinical studies, one verified “ALS reversal” occurred in a person using a combination of alternative therapies which included astaxanthin. There have been no trials of astaxanthin in people living with ALS. Natural astaxanthin appears to be safe and inexpensive. Based on the above information, we support further pre-clinical and/or clinical trials of astaxanthin in disease models and PALS, respectively, to further elucidate efficacy.

Original language	English (US)
Pages (from-to)	553-557
Number of pages	5
Journal	Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Volume	24
Issue number	5-6
DOIs	https://doi.org/10.1080/21678421.2023.2171302
State	Published - 2023

Keywords

Amyotrophic lateral sclerosis
alternative therapy
astaxanthin
neurodegeneration
oxidative stress

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1080/21678421.2023.2171302

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Fullam, T., Armon, C., Barkhaus, P., Barnes, B., Beauchamp, M., Benatar, M., Bertorini, T., Bowser, R., Bromberg, M., Mascias Cadavid, J., Carter, G. T., Dimachkie, M., Ennist, D., Feldman, E. L., Heiman-patterson, T., Jhooty, S., Lund, I., Mcdermott, C., Pattee, G., ... Bedlack, R. (2023). ALSUntangled # 69: astaxanthin. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24(5-6), 553-557. https://doi.org/10.1080/21678421.2023.2171302

Fullam, T, Armon, C, Barkhaus, P, Barnes, B, Beauchamp, M, Benatar, M, Bertorini, T, Bowser, R, Bromberg, M, Mascias Cadavid, J, Carter, GT, Dimachkie, M, Ennist, D, Feldman, EL, Heiman-patterson, T, Jhooty, S, Lund, I, Mcdermott, C, Pattee, G, Ratner, D, Wicks, P & Bedlack, R 2023, 'ALSUntangled # 69: astaxanthin', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol. 24, no. 5-6, pp. 553-557. https://doi.org/10.1080/21678421.2023.2171302

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abstract = "ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review astaxanthin which has plausible mechanisms for slowing ALS progression including antioxidant, anti-inflammatory, and anti-apoptotic effects. While there are no ALS-specific pre-clinical studies, one verified “ALS reversal” occurred in a person using a combination of alternative therapies which included astaxanthin. There have been no trials of astaxanthin in people living with ALS. Natural astaxanthin appears to be safe and inexpensive. Based on the above information, we support further pre-clinical and/or clinical trials of astaxanthin in disease models and PALS, respectively, to further elucidate efficacy.",

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doi = "10.1080/21678421.2023.2171302",

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AU - Barnes, Benjamin

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AU - Benatar, Michael

AU - Bertorini, Tulio

AU - Bowser, Robert

AU - Bromberg, Mark

AU - Mascias Cadavid, Javier

AU - Carter, Gregory T.

AU - Dimachkie, Mazen

AU - Ennist, Dave

AU - Feldman, Eva L.

AU - Heiman-patterson, Terry

AU - Jhooty, Sartaj

AU - Lund, Isaac

AU - Mcdermott, Christopher

AU - Pattee, Gary

AU - Ratner, Dylan

AU - Wicks, Paul

AU - Bedlack, Richard

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ALSUntangled # 69: astaxanthin

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