Alveolar ridge augmentation in Macaca fascicularis using polysulfone with and without demineralized bone powder

Fouad Salama, Mohamed M.H. Sharawy

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The purpose of this study was to test the soft tissue and bone response to the implantation of porous polysulfone (PPSF) with and without demineralized bone powder (DBP) for ridge augmentation in Macaca fascicularis. The mandibular molar teeth were extracted in five adult female monkeys, followed by massive alveolectomy. Five to eight months later, PPSF + DBP was inserted subperiosteally on the left side, while PPSF alone was inserted on the right side. The animals were killed 42, 60, and 90 days following implantation. Specimens were processed for light microscopy, scanning electron microscopy, tetracycline labeling, and histomorphometric measurement of new bone. The 42-day specimens of the PPSF + DBP and PPSF revealed penetration of fibrous tissue rich in fibroblasts and blood vessels into the pores of the PPSF. At 60 and 90 days, the PPSF side showed organized fibrous tissue, but bone grew only for a short distance into the implant. In contrast, the PPSF + DBP side showed large amounts of bone formation, and bone almost covered the implant. The qualitative results were confirmed by histomorphometric examination.

Original languageEnglish (US)
Pages (from-to)1169-1176
Number of pages8
JournalJournal of Oral and Maxillofacial Surgery
Volume47
Issue number11
DOIs
StatePublished - Jan 1 1989

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Alveolar Ridge Augmentation
Macaca fascicularis
Powders
Bone and Bones
Alveolectomy
polysulfone P 1700
Tetracycline
Osteogenesis
Electron Scanning Microscopy
Haplorhini
Blood Vessels
Microscopy
Tooth
Fibroblasts
Light

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

Cite this

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title = "Alveolar ridge augmentation in Macaca fascicularis using polysulfone with and without demineralized bone powder",
abstract = "The purpose of this study was to test the soft tissue and bone response to the implantation of porous polysulfone (PPSF) with and without demineralized bone powder (DBP) for ridge augmentation in Macaca fascicularis. The mandibular molar teeth were extracted in five adult female monkeys, followed by massive alveolectomy. Five to eight months later, PPSF + DBP was inserted subperiosteally on the left side, while PPSF alone was inserted on the right side. The animals were killed 42, 60, and 90 days following implantation. Specimens were processed for light microscopy, scanning electron microscopy, tetracycline labeling, and histomorphometric measurement of new bone. The 42-day specimens of the PPSF + DBP and PPSF revealed penetration of fibrous tissue rich in fibroblasts and blood vessels into the pores of the PPSF. At 60 and 90 days, the PPSF side showed organized fibrous tissue, but bone grew only for a short distance into the implant. In contrast, the PPSF + DBP side showed large amounts of bone formation, and bone almost covered the implant. The qualitative results were confirmed by histomorphometric examination.",
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N2 - The purpose of this study was to test the soft tissue and bone response to the implantation of porous polysulfone (PPSF) with and without demineralized bone powder (DBP) for ridge augmentation in Macaca fascicularis. The mandibular molar teeth were extracted in five adult female monkeys, followed by massive alveolectomy. Five to eight months later, PPSF + DBP was inserted subperiosteally on the left side, while PPSF alone was inserted on the right side. The animals were killed 42, 60, and 90 days following implantation. Specimens were processed for light microscopy, scanning electron microscopy, tetracycline labeling, and histomorphometric measurement of new bone. The 42-day specimens of the PPSF + DBP and PPSF revealed penetration of fibrous tissue rich in fibroblasts and blood vessels into the pores of the PPSF. At 60 and 90 days, the PPSF side showed organized fibrous tissue, but bone grew only for a short distance into the implant. In contrast, the PPSF + DBP side showed large amounts of bone formation, and bone almost covered the implant. The qualitative results were confirmed by histomorphometric examination.

AB - The purpose of this study was to test the soft tissue and bone response to the implantation of porous polysulfone (PPSF) with and without demineralized bone powder (DBP) for ridge augmentation in Macaca fascicularis. The mandibular molar teeth were extracted in five adult female monkeys, followed by massive alveolectomy. Five to eight months later, PPSF + DBP was inserted subperiosteally on the left side, while PPSF alone was inserted on the right side. The animals were killed 42, 60, and 90 days following implantation. Specimens were processed for light microscopy, scanning electron microscopy, tetracycline labeling, and histomorphometric measurement of new bone. The 42-day specimens of the PPSF + DBP and PPSF revealed penetration of fibrous tissue rich in fibroblasts and blood vessels into the pores of the PPSF. At 60 and 90 days, the PPSF side showed organized fibrous tissue, but bone grew only for a short distance into the implant. In contrast, the PPSF + DBP side showed large amounts of bone formation, and bone almost covered the implant. The qualitative results were confirmed by histomorphometric examination.

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