TY - JOUR
T1 - Aminoisoquinolines as colorimetric Hg2+ sensors
T2 - the importance of molecular structure and sacrificial base
AU - Wan, Yanjun
AU - Niu, Weijun
AU - Behof, William J.
AU - Wang, Yifei
AU - Boyle, Paul
AU - Gorman, Christopher B.
N1 - Funding Information:
We would like to thank Dr. Lin He for suggestions on fluorescence measurements. This work was supported by the Department of Energy (Grant DE-FG02-05ER46238). Mass spectra were obtained at the NCSU Department of Chemistry Mass Spectrometry Facility. Funding was obtained from the North Carolina Biotechnology Center, and the NCSU Department of Chemistry.
PY - 2009/5/30
Y1 - 2009/5/30
N2 - Here it is shown that 3-phenyl-2-amino isoquinoline acts as a simple mercury sensor. It is simple to synthesize. The molecule requires base/buffer to bind in a 1:1 stoichiometry with mercury ion, however. Otherwise, it acts as a sacrificial base, presumably to pick up a proton liberated during binding. This binding is characterized quantitatively.
AB - Here it is shown that 3-phenyl-2-amino isoquinoline acts as a simple mercury sensor. It is simple to synthesize. The molecule requires base/buffer to bind in a 1:1 stoichiometry with mercury ion, however. Otherwise, it acts as a sacrificial base, presumably to pick up a proton liberated during binding. This binding is characterized quantitatively.
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U2 - 10.1016/j.tet.2009.03.063
DO - 10.1016/j.tet.2009.03.063
M3 - Article
AN - SCOPUS:65249113812
SN - 0040-4020
VL - 65
SP - 4293
EP - 4297
JO - Tetrahedron
JF - Tetrahedron
IS - 22
ER -