Amnesia After Unilateral Temporal Lobectomy: A Case Report

David W. Loring, Bruce P. Hermann, Kimford J. Meador, Gregory P Lee, Brian B. Gallagher, Don W. King, Anthony M Murro, Joseph R. Smith, Allen R. Wyler

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Summary: We report a mixed handed (L>R) patient with exclusive right cerebral language representation who de–veloped a permanent anterograde amnestic syndrome after right anterotemporal lobectomy. Preoperative neuropsychological performance consisted of impaired verbal memory and normal nonverbal memory. Wada memory performance was asymmetrical for objects presented soon after amobarbital injection in conjunction with no memory asymmetry for items presented later in the Wada evaluation. Preand postoperative magnetic resonance imaging (MRI) scans showed no structural lesions; however, postoperative MRI hippocampal volume measurements suggested decreased hippocampal volume for the nonresected temporal lobe. These results confirm the risk of anterograde amnesia after unilateral temporal lobectomy and demonstrate that baseline neuropsychological testing may falsely literalize material‐specific memory functions in patients with atypical cerebral language dominance.

Original languageEnglish (US)
Pages (from-to)757-763
Number of pages7
JournalEpilepsia
Volume35
Issue number4
DOIs
StatePublished - Jan 1 1994

Fingerprint

Amnesia
Language
Anterograde Amnesia
Magnetic Resonance Imaging
Cerebral Dominance
Amobarbital
Temporal Lobe
Injections

Keywords

  • Amnesia
  • Epilepsy
  • Neurosurgery
  • Temporallobe
  • Wada test

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Loring, D. W., Hermann, B. P., Meador, K. J., Lee, G. P., Gallagher, B. B., King, D. W., ... Wyler, A. R. (1994). Amnesia After Unilateral Temporal Lobectomy: A Case Report. Epilepsia, 35(4), 757-763. https://doi.org/10.1111/j.1528-1157.1994.tb02507.x

Amnesia After Unilateral Temporal Lobectomy : A Case Report. / Loring, David W.; Hermann, Bruce P.; Meador, Kimford J.; Lee, Gregory P; Gallagher, Brian B.; King, Don W.; Murro, Anthony M; Smith, Joseph R.; Wyler, Allen R.

In: Epilepsia, Vol. 35, No. 4, 01.01.1994, p. 757-763.

Research output: Contribution to journalArticle

Loring, DW, Hermann, BP, Meador, KJ, Lee, GP, Gallagher, BB, King, DW, Murro, AM, Smith, JR & Wyler, AR 1994, 'Amnesia After Unilateral Temporal Lobectomy: A Case Report', Epilepsia, vol. 35, no. 4, pp. 757-763. https://doi.org/10.1111/j.1528-1157.1994.tb02507.x
Loring DW, Hermann BP, Meador KJ, Lee GP, Gallagher BB, King DW et al. Amnesia After Unilateral Temporal Lobectomy: A Case Report. Epilepsia. 1994 Jan 1;35(4):757-763. https://doi.org/10.1111/j.1528-1157.1994.tb02507.x
Loring, David W. ; Hermann, Bruce P. ; Meador, Kimford J. ; Lee, Gregory P ; Gallagher, Brian B. ; King, Don W. ; Murro, Anthony M ; Smith, Joseph R. ; Wyler, Allen R. / Amnesia After Unilateral Temporal Lobectomy : A Case Report. In: Epilepsia. 1994 ; Vol. 35, No. 4. pp. 757-763.
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