Amobarbital dose effects on Wada memory testing

David W. Loring, Kimford J. Meador, Gregory P. Lee

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We investigated the relationship of amobarbital dosage to Wada memory performance in 72 patients who have subsequently undergone unilateral anterior temporal lobectomy (left, 39; right, 33). Significantly poorer recognition memory performance following injection ipsilateral to the seizure focus was associated with higher amobarbital dosage administration (r = -0.40; p <0.001). Patients were also dichotomized into "low" (125 mg and lower) and "high" (greater than 125 mg) dosage groups based on ipsilateral dosage, and significantly poorer recognition memory performance (p < 0.001) was observed following higher amobarbital administration. These data demonstrate that amobarbital dosage is one factor that contributes to memory performance during the Wada test.

Original languageEnglish (US)
Pages (from-to)171-174
Number of pages4
JournalJournal of Epilepsy
Volume5
Issue number3
DOIs
StatePublished - 1992

Fingerprint

Amobarbital
Anterior Temporal Lobectomy
Seizures
Injections
Recognition (Psychology)

Keywords

  • Amobarbital
  • Epilepsy
  • Memory
  • Temporal lobectomy
  • Wada test

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Amobarbital dose effects on Wada memory testing. / Loring, David W.; Meador, Kimford J.; Lee, Gregory P.

In: Journal of Epilepsy, Vol. 5, No. 3, 1992, p. 171-174.

Research output: Contribution to journalArticle

Loring, David W. ; Meador, Kimford J. ; Lee, Gregory P. / Amobarbital dose effects on Wada memory testing. In: Journal of Epilepsy. 1992 ; Vol. 5, No. 3. pp. 171-174.
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