Amphiphilic gels with controlled mesh dimensions for insulin delivery

Joseph P. Kennedy, Georgina Fenyvesi, Shuo Na, Balazs Keszler, Kenneth S. Rosenthal

Research output: Contribution to journalConference article

5 Scopus citations

Abstract

A new process has been developed for the preparation of tubular amphiphilic networks of poly(N,N-dimethyl acrylamide) (PDMAm) crosslinked by polyisobutylene (PIB), suitable for implantation and immunoisolation of pancreatic tissue. The pores can be controlled by fine tuning the molecular weight of the PDMAm so as to allow the diffusion of glucose and insulin but interdict the ingress of larger immunoglobulins.

Original languageEnglish (US)
Pages (from-to)710-711
Number of pages2
JournalAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume41
Issue number1
Publication statusPublished - Mar 1 2000
Externally publishedYes
EventThe San Francisco Meeting - San Francisco, CA, USA
Duration: Mar 26 2000Mar 31 2000

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ASJC Scopus subject areas

  • Polymers and Plastics

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