An improved internal mammary irradiation technique in radiation treatment of locally advanced breast cancers.

Jian Yue Jin, Eric E. Klein, Feng Ming Kong, Zuofeng Li

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The purpose of the present study was to compare a new internal mammary irradiation technique with traditional techniques for locally advanced breast cancers in terms of sparing ipsilateral lung and heart and reducing the "cold" and "hot spots"in breast tissue. The new technique uses wide tangential fields for the first eight fractions of treatment. A medial internal mammary field (IMF) of electrons matched with narrowed tangential fields is used for the remaining fractions. Intensity-modulated radiation therapy (IMRT) by means of segmented multileaf collimation (SMLC) is used in the narrowed tangential fields to improve the match between the electron and the photon fields. Treatment planning was performed to compare this technique to a wide-tangential-only technique and to a traditional oblique IMF technique for three patients with differing habitus. Film dosimetry was performed in a solid water phantom to confirm the planning results. For all three patients, the mean doses of the ipsilateral lung and the heart were significantly reduced with the new technique. The lung and the heart volumes were remarkably reduced at lowdose levels (< or =12 Gy) compared to the traditional IMF technique, and significantly reduced at all dose levels compared to the wide tangential technique. The new technique also reduced the "cold" and "hot spots" along the match plane between the IMF and the tangential fields compared to the traditional IMF technique. In conclusion, the new IMF technique shows dosimetric improvement compared to the traditional IMF technique in terms of the critical organ sparing and target dose uniformity.

Original languageEnglish (US)
Pages (from-to)84-93
Number of pages10
JournalJournal of applied clinical medical physics / American College of Medical Physics
Volume6
Issue number1
DOIs
StatePublished - Jan 1 2005

Fingerprint

breast
lungs
Breast
cancer
Irradiation
Radiation
Breast Neoplasms
dosage
irradiation
planning
radiation
Planning
Electrons
Radiotherapy
collimation
organs
Dosimetry
dosimeters
radiation therapy
electrons

ASJC Scopus subject areas

  • Radiation
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

Cite this

An improved internal mammary irradiation technique in radiation treatment of locally advanced breast cancers. / Jin, Jian Yue; Klein, Eric E.; Kong, Feng Ming; Li, Zuofeng.

In: Journal of applied clinical medical physics / American College of Medical Physics, Vol. 6, No. 1, 01.01.2005, p. 84-93.

Research output: Contribution to journalArticle

@article{c953dc230a334178b974fe1e9ac9a460,
title = "An improved internal mammary irradiation technique in radiation treatment of locally advanced breast cancers.",
abstract = "The purpose of the present study was to compare a new internal mammary irradiation technique with traditional techniques for locally advanced breast cancers in terms of sparing ipsilateral lung and heart and reducing the {"}cold{"} and {"}hot spots{"}in breast tissue. The new technique uses wide tangential fields for the first eight fractions of treatment. A medial internal mammary field (IMF) of electrons matched with narrowed tangential fields is used for the remaining fractions. Intensity-modulated radiation therapy (IMRT) by means of segmented multileaf collimation (SMLC) is used in the narrowed tangential fields to improve the match between the electron and the photon fields. Treatment planning was performed to compare this technique to a wide-tangential-only technique and to a traditional oblique IMF technique for three patients with differing habitus. Film dosimetry was performed in a solid water phantom to confirm the planning results. For all three patients, the mean doses of the ipsilateral lung and the heart were significantly reduced with the new technique. The lung and the heart volumes were remarkably reduced at lowdose levels (< or =12 Gy) compared to the traditional IMF technique, and significantly reduced at all dose levels compared to the wide tangential technique. The new technique also reduced the {"}cold{"} and {"}hot spots{"} along the match plane between the IMF and the tangential fields compared to the traditional IMF technique. In conclusion, the new IMF technique shows dosimetric improvement compared to the traditional IMF technique in terms of the critical organ sparing and target dose uniformity.",
author = "Jin, {Jian Yue} and Klein, {Eric E.} and Kong, {Feng Ming} and Zuofeng Li",
year = "2005",
month = "1",
day = "1",
doi = "10.1120/jacmp.v6i1.2079",
language = "English (US)",
volume = "6",
pages = "84--93",
journal = "Journal of applied clinical medical physics / American College of Medical Physics",
issn = "1526-9914",
publisher = "American Institute of Physics Publising LLC",
number = "1",

}

TY - JOUR

T1 - An improved internal mammary irradiation technique in radiation treatment of locally advanced breast cancers.

AU - Jin, Jian Yue

AU - Klein, Eric E.

AU - Kong, Feng Ming

AU - Li, Zuofeng

PY - 2005/1/1

Y1 - 2005/1/1

N2 - The purpose of the present study was to compare a new internal mammary irradiation technique with traditional techniques for locally advanced breast cancers in terms of sparing ipsilateral lung and heart and reducing the "cold" and "hot spots"in breast tissue. The new technique uses wide tangential fields for the first eight fractions of treatment. A medial internal mammary field (IMF) of electrons matched with narrowed tangential fields is used for the remaining fractions. Intensity-modulated radiation therapy (IMRT) by means of segmented multileaf collimation (SMLC) is used in the narrowed tangential fields to improve the match between the electron and the photon fields. Treatment planning was performed to compare this technique to a wide-tangential-only technique and to a traditional oblique IMF technique for three patients with differing habitus. Film dosimetry was performed in a solid water phantom to confirm the planning results. For all three patients, the mean doses of the ipsilateral lung and the heart were significantly reduced with the new technique. The lung and the heart volumes were remarkably reduced at lowdose levels (< or =12 Gy) compared to the traditional IMF technique, and significantly reduced at all dose levels compared to the wide tangential technique. The new technique also reduced the "cold" and "hot spots" along the match plane between the IMF and the tangential fields compared to the traditional IMF technique. In conclusion, the new IMF technique shows dosimetric improvement compared to the traditional IMF technique in terms of the critical organ sparing and target dose uniformity.

AB - The purpose of the present study was to compare a new internal mammary irradiation technique with traditional techniques for locally advanced breast cancers in terms of sparing ipsilateral lung and heart and reducing the "cold" and "hot spots"in breast tissue. The new technique uses wide tangential fields for the first eight fractions of treatment. A medial internal mammary field (IMF) of electrons matched with narrowed tangential fields is used for the remaining fractions. Intensity-modulated radiation therapy (IMRT) by means of segmented multileaf collimation (SMLC) is used in the narrowed tangential fields to improve the match between the electron and the photon fields. Treatment planning was performed to compare this technique to a wide-tangential-only technique and to a traditional oblique IMF technique for three patients with differing habitus. Film dosimetry was performed in a solid water phantom to confirm the planning results. For all three patients, the mean doses of the ipsilateral lung and the heart were significantly reduced with the new technique. The lung and the heart volumes were remarkably reduced at lowdose levels (< or =12 Gy) compared to the traditional IMF technique, and significantly reduced at all dose levels compared to the wide tangential technique. The new technique also reduced the "cold" and "hot spots" along the match plane between the IMF and the tangential fields compared to the traditional IMF technique. In conclusion, the new IMF technique shows dosimetric improvement compared to the traditional IMF technique in terms of the critical organ sparing and target dose uniformity.

UR - http://www.scopus.com/inward/record.url?scp=85024950977&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85024950977&partnerID=8YFLogxK

U2 - 10.1120/jacmp.v6i1.2079

DO - 10.1120/jacmp.v6i1.2079

M3 - Article

C2 - 15770199

AN - SCOPUS:85024950977

VL - 6

SP - 84

EP - 93

JO - Journal of applied clinical medical physics / American College of Medical Physics

JF - Journal of applied clinical medical physics / American College of Medical Physics

SN - 1526-9914

IS - 1

ER -