An unconventional role of neurotransmission in synapse formation

Wencheng Xiong, Lin Mei

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Abstract

How do presynatic inputs regulate synapse formation? In this issue of Neuron, Lin et al. show that the neurotransmitter acetylcholine decreases the stability of AChR clusters. This dispersing activity, which requires the serine/threonine kinase Cdk5, cooperates with positive signals from motoneurons to ensure high concentration of AChRs at the neuromuscular junction.

Original languageEnglish (US)
Pages (from-to)521-523
Number of pages3
JournalNeuron
Volume46
Issue number4
DOIs
StatePublished - May 19 2005

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Neuromuscular Junction
Protein-Serine-Threonine Kinases
Motor Neurons
Synaptic Transmission
Synapses
Acetylcholine
Neurotransmitter Agents
Neurons

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

An unconventional role of neurotransmission in synapse formation. / Xiong, Wencheng; Mei, Lin.

In: Neuron, Vol. 46, No. 4, 19.05.2005, p. 521-523.

Research output: Contribution to journalShort survey

Xiong, Wencheng ; Mei, Lin. / An unconventional role of neurotransmission in synapse formation. In: Neuron. 2005 ; Vol. 46, No. 4. pp. 521-523.
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