An updated, user-friendly guide to genotype interpretation

Research output: Contribution to journalReview article

8 Scopus citations

Abstract

Genotypic antiretroviral resistance testing (GART) has been shown to be of value in selecting antiretroviral therapy. Unfortunately, GART reports often are difficult to interpret and, at times, can be misleading. Published lists of 'primary' resistance mutations often do not include the combinations of 'secondary' mutations, which also limit the efficacy of antiretroviral agents. This article tries to rectify this situation by introducing a general approach to genotype interpretation and by providing more 'user-friendly' tables of key single mutations and key mutation combinations.

Original languageEnglish (US)
Pages (from-to)652-657
Number of pages6
JournalAIDS Reader
Volume10
Issue number11
StatePublished - Jan 1 2000
Externally publishedYes

Keywords

  • Antiretroviral resistance mutations
  • Genotype interpretation

ASJC Scopus subject areas

  • Infectious Diseases

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