Analysis of Suicide Risk in Patients with Penile Cancer and Review of the Literature

William G. Simpson, Zachary W A Klaassen, Rita P. Jen, William M. Hughes, Durwood Earnest Neal, Martha Kennedy Terris

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

The treatment for penile cancer has been shown to cause harmful psychiatric symptoms as well as have detrimental effects on well-being. In the past several years, alternatives to total or partial penectomy have emerged, such as chemotherapy, radiation, penile sparing, and laser ablation therapies. A more specific breakdown for penile cancer is in order as the therapy has the potential for life changing surgery. We examined the Surveillance, Epidemiology, and End Results (SEER) database (1973-2013), comprising 28% of the United States population. International Classification of Diseases, Tenth revision codes C60.8-C60.9 and the International Classification of Diseases-Oncology codes 8010/2, 8010/3, 8051/2, 8051/3, 8052/2, 8052/3, 8070/2, 8070/3-8072/3, 8074/3, 8076/3, and 8083/3-8084/3 were used. Age, race, marital status, and clinicopathologic variables were studied. We used contingency tables of suicide rates; mid-P exact test was used for analysis. There were 13 suicides noted in 6155 patients with squamous cell carcinoma of the penis. All patients that committed suicide had undergone a surgical intervention. Certainly, penile cancer after treatment has a powerful effect on quality of life as increased depression and sexual anxiety have been documented in postoperative patients. This is in contrast to the observed suicide rate. Despite the reported negative psychological effects in patients with penile cancer, suicide rates are among the lowest of all urologic malignancies.

Original languageEnglish (US)
Pages (from-to)e257-e261
JournalClinical Genitourinary Cancer
Volume16
Issue number2
DOIs
StatePublished - Apr 1 2018

Fingerprint

Penile Neoplasms
Suicide
Laser Therapy
International Classification of Diseases
Penis
Marital Status
Psychiatry
Squamous Cell Carcinoma
Epidemiology
Therapeutics
Anxiety
Quality of Life
Databases
Radiation
Depression
Psychology
Drug Therapy
Population
Neoplasms

Keywords

  • Depression
  • Malignacy
  • Penectomy
  • Penile-sparing
  • Psychiatric

ASJC Scopus subject areas

  • Oncology
  • Urology

Cite this

Analysis of Suicide Risk in Patients with Penile Cancer and Review of the Literature. / Simpson, William G.; Klaassen, Zachary W A; Jen, Rita P.; Hughes, William M.; Neal, Durwood Earnest; Terris, Martha Kennedy.

In: Clinical Genitourinary Cancer, Vol. 16, No. 2, 01.04.2018, p. e257-e261.

Research output: Contribution to journalReview article

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