Antenatal diagnosis and early surgery for choledochal cyst

Charles G Howell, John M. Templeton, Stuart Weiner, Mark Glassman, James M. Betts, C. L. Witzleben

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

The pathogenesis and optimal treatment of choledochal cyst have long remained questions of considerable speculation and dispute. Because the pregnancy of a 37-year-old woman was felt to be at risk, five antenatal ultrasound examinations were made. The fourth examination at 31.5 weeks of gestation demonstrated a choledochal cyst. Following birth, the child was studied with repeat ultrasound examinations and scintigraphy. The results of these studies plus the findings at surgery contributed new evidence regarding the possible pathogenesis and optimal treatment of choledochal cysts. Although the time at which the cyst originated is compatible with the concept of reflux of pancreatic juice into the common duct, no abnormal junction of the pancreatic and common duct was identified. No evidence of obstruction as part of the pathogenesis could be demonstrated. Progressive changes in the choledochal cyst in the first ten days of life suggested that delay in diagnosis and treatment of a choledochal cyst may contribute to early complications such as cholangitis. Early excision of the cyst in the newborn is considered to be the optimal treatment and may pose less risk to the patient than delayed surgical exploration.

Original languageEnglish (US)
Pages (from-to)387-393
Number of pages7
JournalJournal of Pediatric Surgery
Volume18
Issue number4
DOIs
StatePublished - Jan 1 1983

Fingerprint

Choledochal Cyst
Prenatal Diagnosis
Cysts
Pancreatic Juice
Pregnancy
Dissent and Disputes
Cholangitis
Pancreatic Ducts
Therapeutics
Radionuclide Imaging
Parturition
Newborn Infant

Keywords

  • Choledochal cyst
  • antenatal ultrasonography

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

Howell, C. G., Templeton, J. M., Weiner, S., Glassman, M., Betts, J. M., & Witzleben, C. L. (1983). Antenatal diagnosis and early surgery for choledochal cyst. Journal of Pediatric Surgery, 18(4), 387-393. https://doi.org/10.1016/S0022-3468(83)80187-0

Antenatal diagnosis and early surgery for choledochal cyst. / Howell, Charles G; Templeton, John M.; Weiner, Stuart; Glassman, Mark; Betts, James M.; Witzleben, C. L.

In: Journal of Pediatric Surgery, Vol. 18, No. 4, 01.01.1983, p. 387-393.

Research output: Contribution to journalArticle

Howell, CG, Templeton, JM, Weiner, S, Glassman, M, Betts, JM & Witzleben, CL 1983, 'Antenatal diagnosis and early surgery for choledochal cyst', Journal of Pediatric Surgery, vol. 18, no. 4, pp. 387-393. https://doi.org/10.1016/S0022-3468(83)80187-0
Howell, Charles G ; Templeton, John M. ; Weiner, Stuart ; Glassman, Mark ; Betts, James M. ; Witzleben, C. L. / Antenatal diagnosis and early surgery for choledochal cyst. In: Journal of Pediatric Surgery. 1983 ; Vol. 18, No. 4. pp. 387-393.
@article{ef9f861b74574970b2a73930dbbed4cf,
title = "Antenatal diagnosis and early surgery for choledochal cyst",
abstract = "The pathogenesis and optimal treatment of choledochal cyst have long remained questions of considerable speculation and dispute. Because the pregnancy of a 37-year-old woman was felt to be at risk, five antenatal ultrasound examinations were made. The fourth examination at 31.5 weeks of gestation demonstrated a choledochal cyst. Following birth, the child was studied with repeat ultrasound examinations and scintigraphy. The results of these studies plus the findings at surgery contributed new evidence regarding the possible pathogenesis and optimal treatment of choledochal cysts. Although the time at which the cyst originated is compatible with the concept of reflux of pancreatic juice into the common duct, no abnormal junction of the pancreatic and common duct was identified. No evidence of obstruction as part of the pathogenesis could be demonstrated. Progressive changes in the choledochal cyst in the first ten days of life suggested that delay in diagnosis and treatment of a choledochal cyst may contribute to early complications such as cholangitis. Early excision of the cyst in the newborn is considered to be the optimal treatment and may pose less risk to the patient than delayed surgical exploration.",
keywords = "Choledochal cyst, antenatal ultrasonography",
author = "Howell, {Charles G} and Templeton, {John M.} and Stuart Weiner and Mark Glassman and Betts, {James M.} and Witzleben, {C. L.}",
year = "1983",
month = "1",
day = "1",
doi = "10.1016/S0022-3468(83)80187-0",
language = "English (US)",
volume = "18",
pages = "387--393",
journal = "Journal of Pediatric Surgery",
issn = "0022-3468",
publisher = "W.B. Saunders Ltd",
number = "4",

}

TY - JOUR

T1 - Antenatal diagnosis and early surgery for choledochal cyst

AU - Howell, Charles G

AU - Templeton, John M.

AU - Weiner, Stuart

AU - Glassman, Mark

AU - Betts, James M.

AU - Witzleben, C. L.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - The pathogenesis and optimal treatment of choledochal cyst have long remained questions of considerable speculation and dispute. Because the pregnancy of a 37-year-old woman was felt to be at risk, five antenatal ultrasound examinations were made. The fourth examination at 31.5 weeks of gestation demonstrated a choledochal cyst. Following birth, the child was studied with repeat ultrasound examinations and scintigraphy. The results of these studies plus the findings at surgery contributed new evidence regarding the possible pathogenesis and optimal treatment of choledochal cysts. Although the time at which the cyst originated is compatible with the concept of reflux of pancreatic juice into the common duct, no abnormal junction of the pancreatic and common duct was identified. No evidence of obstruction as part of the pathogenesis could be demonstrated. Progressive changes in the choledochal cyst in the first ten days of life suggested that delay in diagnosis and treatment of a choledochal cyst may contribute to early complications such as cholangitis. Early excision of the cyst in the newborn is considered to be the optimal treatment and may pose less risk to the patient than delayed surgical exploration.

AB - The pathogenesis and optimal treatment of choledochal cyst have long remained questions of considerable speculation and dispute. Because the pregnancy of a 37-year-old woman was felt to be at risk, five antenatal ultrasound examinations were made. The fourth examination at 31.5 weeks of gestation demonstrated a choledochal cyst. Following birth, the child was studied with repeat ultrasound examinations and scintigraphy. The results of these studies plus the findings at surgery contributed new evidence regarding the possible pathogenesis and optimal treatment of choledochal cysts. Although the time at which the cyst originated is compatible with the concept of reflux of pancreatic juice into the common duct, no abnormal junction of the pancreatic and common duct was identified. No evidence of obstruction as part of the pathogenesis could be demonstrated. Progressive changes in the choledochal cyst in the first ten days of life suggested that delay in diagnosis and treatment of a choledochal cyst may contribute to early complications such as cholangitis. Early excision of the cyst in the newborn is considered to be the optimal treatment and may pose less risk to the patient than delayed surgical exploration.

KW - Choledochal cyst

KW - antenatal ultrasonography

UR - http://www.scopus.com/inward/record.url?scp=0020518241&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020518241&partnerID=8YFLogxK

U2 - 10.1016/S0022-3468(83)80187-0

DO - 10.1016/S0022-3468(83)80187-0

M3 - Article

VL - 18

SP - 387

EP - 393

JO - Journal of Pediatric Surgery

JF - Journal of Pediatric Surgery

SN - 0022-3468

IS - 4

ER -