Anticoagulation dilemma in a high-risk patient with On-X valves

Ami M. Karkar, Manuel R. Castresana, Nadine Odo, Shvetank Agarwal

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Thromboembolism continues to be a major concern in patients with mechanical heart valves, especially in those with unsatisfactory anticoagulation levels. The new On-X valve (On-X Life Technologies, Austin, TX, USA) has been reported as having unique structural characteristics that offer lower thrombogenicity to the valve. We report a case where the patient received no or minimal systemic anticoagulation after placement of On-X mitral and aortic valves due to development of severe mucosal arterio-venous malformations yet did not show any evidence of thromboembolism. This case report reinforces the findings of recent studies that lower anticoagulation levels may be acceptable in patients with On-X valves and suggests this valve may be particularly useful in those in whom therapeutic levels of anticoagulation cannot be achieved due to increased risk of bleeding.

Original languageEnglish (US)
Pages (from-to)257-260
Number of pages4
JournalAnnals of Cardiac Anaesthesia
Volume18
Issue number2
DOIs
StatePublished - Feb 1 2015

Keywords

  • Anticoagulation
  • On-X valve
  • Thromboembolism

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine

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