Antidepressant activity of brahmi in albino mice

Sldv Ramana Murty Kadali, M. C. Das, Arni S R Rao, Sri G. Karuna

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Context: In traditional system of medicine brahmi has been used to enhance memory. Recently it has been reported to have action in psychiatric disorders. With these backgrounds the work has been undertaken to study antidepressant activity of brahmi in albino mice. Aim: To evaluate antidepressant activity of brahmi in experimental models. Materials and Methods: The antidepressant activity was studied in albino mice using forced swimming test (FST), tail suspension test (TST) and shock induced depression (SID). Imipramine (10mg/kg), fluoxetine (30mg/kg) were used as standard drugs and brahmi (10, 20, 30mg/kg) was used as test drug. Results: Brahmi exhibited significant decrease in duration of immobility in FST and reduced the shock induced decrease in activity in SID models. It didn't show any activity in the TST model. Conclusion: Brahmi has shown antidepressant activity in FST and SID.

Original languageEnglish (US)
Pages (from-to)35-37
Number of pages3
JournalJournal of Clinical and Diagnostic Research
Volume8
Issue number3
DOIs
StatePublished - Mar 15 2014

Fingerprint

Antidepressive Agents
Shock
Hindlimb Suspension
Depression
Suspensions
Imipramine
Fluoxetine
Traditional Medicine
Systems Analysis
Pharmaceutical Preparations
Medicine
Psychiatry
Theoretical Models
Data storage equipment
Swimming

Keywords

  • Antidepressant activity
  • Brahmi
  • Forced swim test
  • Tail suspension test

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Antidepressant activity of brahmi in albino mice. / Murty Kadali, Sldv Ramana; Das, M. C.; Rao, Arni S R; Karuna, Sri G.

In: Journal of Clinical and Diagnostic Research, Vol. 8, No. 3, 15.03.2014, p. 35-37.

Research output: Contribution to journalArticle

Murty Kadali, Sldv Ramana ; Das, M. C. ; Rao, Arni S R ; Karuna, Sri G. / Antidepressant activity of brahmi in albino mice. In: Journal of Clinical and Diagnostic Research. 2014 ; Vol. 8, No. 3. pp. 35-37.
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