Applications of Chemical Ligation in Peptide Synthesis via Acyl Transfer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The utility of native chemical ligation (NCL) in the solution or solid phase synthesis of peptides, cyclic peptides, glycopeptides, and neoglycoconjugates is reviewed. In addition, the mechanistic details of inter- or intra-molecular NCLs are discussed from experimental and computational points of view.

Original languageEnglish (US)
Pages (from-to)229-65
Number of pages37
JournalTopics in Current Chemistry
Volume362
DOIs
StatePublished - 2015

Fingerprint

Cyclic Peptides
Glycopeptides
Peptides

Keywords

  • Acylation
  • Molecular Structure
  • Peptides
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

Cite this

Applications of Chemical Ligation in Peptide Synthesis via Acyl Transfer. / Panda, Siva S.

In: Topics in Current Chemistry, Vol. 362, 2015, p. 229-65.

Research output: Contribution to journalArticle

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abstract = "The utility of native chemical ligation (NCL) in the solution or solid phase synthesis of peptides, cyclic peptides, glycopeptides, and neoglycoconjugates is reviewed. In addition, the mechanistic details of inter- or intra-molecular NCLs are discussed from experimental and computational points of view.",
keywords = "Acylation, Molecular Structure, Peptides, Journal Article, Research Support, Non-U.S. Gov't, Review",
author = "Panda, {Siva S}",
year = "2015",
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AB - The utility of native chemical ligation (NCL) in the solution or solid phase synthesis of peptides, cyclic peptides, glycopeptides, and neoglycoconjugates is reviewed. In addition, the mechanistic details of inter- or intra-molecular NCLs are discussed from experimental and computational points of view.

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KW - Molecular Structure

KW - Peptides

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

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DO - 10.1007/128_2014_608

M3 - Article

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JO - Topics in Current Chemistry

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