Arachidonic acid facilitates experimental chronic osteomyelitis in rats

J. P. Rissing; T. B. Buxton; J. Fisher; R. Harris; R. K. Shockley

doi:10.1128/iai.49.1.141-144.1985

Arachidonic acid facilitates experimental chronic osteomyelitis in rats

J. P. Rissing, T. B. Buxton, J. Fisher, R. Harris, R. K. Shockley

Infectious Disease

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Arachidonic acid was used as a facilitating agent in experimental rat Staphylococcus aureus osteomyelitis and compared with the more commonly used agent, sodium morrhuate. The injection of arachidonic acid or sodium morrhuate and S. aureus into rat tibiae caused increased quantitative bacterial bone counts, gross bone pathology, roentgenographic changes, and weight loss. The doses required to produce these changes appeared to be lower for arachidonic acid.

Original language	English (US)
Pages (from-to)	141-144
Number of pages	4
Journal	Infection and Immunity
Volume	49
Issue number	1
DOIs	https://doi.org/10.1128/iai.49.1.141-144.1985
State	Published - 1985

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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10.1128/iai.49.1.141-144.1985

Cite this

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Arachidonic acid facilitates experimental chronic osteomyelitis in rats

Abstract

ASJC Scopus subject areas

UN SDGs

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