Arachidonic acid facilitates experimental chronic osteomyelitis in rats

J. P. Rissing, T. B. Buxton, John Fremont Fisher, R. Harris, R. K. Shockley

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Arachidonic acid was used as a facilitating agent in experimental rat Staphylococcus aureus osteomyelitis and compared with the more commonly used agent, sodium morrhuate. The injection of arachidonic acid or sodium morrhuate and S. aureus into rat tibiae caused increased quantitative bacterial bone counts, gross bone pathology, roentgenographic changes, and weight loss. The doses required to produce these changes appeared to be lower for arachidonic acid.

Original languageEnglish (US)
Pages (from-to)141-144
Number of pages4
JournalInfection and Immunity
Volume49
Issue number1
StatePublished - Aug 28 1985

Fingerprint

Sodium Morrhuate
Osteomyelitis
Arachidonic Acid
Staphylococcus aureus
Bone and Bones
Bacterial Load
Tibia
Weight Loss
Pathology
Injections

ASJC Scopus subject areas

  • Immunology

Cite this

Arachidonic acid facilitates experimental chronic osteomyelitis in rats. / Rissing, J. P.; Buxton, T. B.; Fisher, John Fremont; Harris, R.; Shockley, R. K.

In: Infection and Immunity, Vol. 49, No. 1, 28.08.1985, p. 141-144.

Research output: Contribution to journalArticle

Rissing, JP, Buxton, TB, Fisher, JF, Harris, R & Shockley, RK 1985, 'Arachidonic acid facilitates experimental chronic osteomyelitis in rats', Infection and Immunity, vol. 49, no. 1, pp. 141-144.
Rissing, J. P. ; Buxton, T. B. ; Fisher, John Fremont ; Harris, R. ; Shockley, R. K. / Arachidonic acid facilitates experimental chronic osteomyelitis in rats. In: Infection and Immunity. 1985 ; Vol. 49, No. 1. pp. 141-144.
@article{b4310f915106492abdae2265ef176974,
title = "Arachidonic acid facilitates experimental chronic osteomyelitis in rats",
abstract = "Arachidonic acid was used as a facilitating agent in experimental rat Staphylococcus aureus osteomyelitis and compared with the more commonly used agent, sodium morrhuate. The injection of arachidonic acid or sodium morrhuate and S. aureus into rat tibiae caused increased quantitative bacterial bone counts, gross bone pathology, roentgenographic changes, and weight loss. The doses required to produce these changes appeared to be lower for arachidonic acid.",
author = "Rissing, {J. P.} and Buxton, {T. B.} and Fisher, {John Fremont} and R. Harris and Shockley, {R. K.}",
year = "1985",
month = "8",
day = "28",
language = "English (US)",
volume = "49",
pages = "141--144",
journal = "Infection and Immunity",
issn = "0019-9567",
publisher = "American Society for Microbiology",
number = "1",

}

TY - JOUR

T1 - Arachidonic acid facilitates experimental chronic osteomyelitis in rats

AU - Rissing, J. P.

AU - Buxton, T. B.

AU - Fisher, John Fremont

AU - Harris, R.

AU - Shockley, R. K.

PY - 1985/8/28

Y1 - 1985/8/28

N2 - Arachidonic acid was used as a facilitating agent in experimental rat Staphylococcus aureus osteomyelitis and compared with the more commonly used agent, sodium morrhuate. The injection of arachidonic acid or sodium morrhuate and S. aureus into rat tibiae caused increased quantitative bacterial bone counts, gross bone pathology, roentgenographic changes, and weight loss. The doses required to produce these changes appeared to be lower for arachidonic acid.

AB - Arachidonic acid was used as a facilitating agent in experimental rat Staphylococcus aureus osteomyelitis and compared with the more commonly used agent, sodium morrhuate. The injection of arachidonic acid or sodium morrhuate and S. aureus into rat tibiae caused increased quantitative bacterial bone counts, gross bone pathology, roentgenographic changes, and weight loss. The doses required to produce these changes appeared to be lower for arachidonic acid.

UR - http://www.scopus.com/inward/record.url?scp=0021854508&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021854508&partnerID=8YFLogxK

M3 - Article

C2 - 3924826

AN - SCOPUS:0021854508

VL - 49

SP - 141

EP - 144

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 1

ER -