Aripiprazole: An appraisal of the translation of complex receptor effects into clinical outcomes

Peter F Buckley, C Simon Sebastian

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Aripiprazole possesses a complex pharmacology with both partial agonist and full antagonist effects. The purpose of this article is to critically review, in the light of its unique receptor pharmacology, the current clinical literature on the use of aripiprazole in the treatment of schizophrenia and mood disorders. There is evidence that aripiprazole is an effective and well tolerated antipsychotic in treating schizophrenia. Now, more recent evidence suggests that aripiprazole may have a role in the treatment of mood disorders. The efficacy side-effect profile of aripiprazole is reviewed herein.

Original languageEnglish (US)
Pages (from-to)699-707
Number of pages9
JournalTherapy
Volume2
Issue number5
DOIs
StatePublished - Sep 1 2005

Keywords

  • Aripiprazole
  • Mood disorders
  • Schizophrenia

ASJC Scopus subject areas

  • Pharmacology (medical)

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