Association among menopause, hormone replacement therapy, and periodontal attachment loss in Southern Brazilian women

Alex N. Haas, Cassiano K. Rosing, Rui V. Oppermann, Jasim M. Albandar, Cristiano Susin

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Background: The aim of the present study was to evaluate the association among menopause, hormone replacement therapy (HRT), and periodontal attachment loss (PAL). Methods: Three hundred twenty-eight women (40 to 69 years old) who participated in a previous oral survey in South Brazil were included. Women who reported not having their monthly menstrual cycles for ≥12 months were classified as postmenopausal. Postmenopausal women were categorized according to HRT. Women with ≥30% teeth with PAL ≥5mm were classified as having periodontitis. The data were analyzed using a multivariable logistic regression model and adjusted for age, smoking, socioeconomic status, and dental care. Results: The prevalence of periodontitis was significantly greater among postmenopausal women not using HRT (HRT-) than among premenopausal women (64.4% versus 46.3%; P = 0.005). Similarly, the multivariable analysis demonstrated a significantly higher chance of having periodontitis in postmenopausal HRT- women than in premenopausal women (odds ratio [OR], 2.1; 95% confidence interval [CI]: 1.1 to 4.0). In contrast, no significant differences were observed in the prevalence of periodontitis between postmenopausal women using HRT (HRT+) and premenopausal women (48.8% versus 46.3%; P = 0.77). After adjusting for cofactors, postmenopausal HRT+ women did not have a greater likelihood of having peri- odontitis than premenopausal women (OR, 1.2; 95% CI: 0.6 to 2.5). No significant differences in tooth loss were observed among the study groups after adjusting for confounders. Conclusions: Postmenopausal HRT- women had a greater chance of having periodontitis than premenopausal women. In contrast, postmenopausal HRT+ women and premeno- pausal women had similar periodontal status. HRT may have a beneficial effect on periodontal health.

Original languageEnglish (US)
Pages (from-to)1380-1387
Number of pages8
JournalJournal of periodontology
Volume80
Issue number9
DOIs
StatePublished - Sep 1 2009

Fingerprint

Periodontal Attachment Loss
Hormone Replacement Therapy
Menopause
Periodontitis
Estrogen Replacement Therapy
Logistic Models
Odds Ratio
Confidence Intervals

Keywords

  • Hormone replacement therapy
  • Menopause
  • Periodontal attachment loss
  • Periodontitis
  • Risk factors
  • Tooth loss

ASJC Scopus subject areas

  • Periodontics

Cite this

Association among menopause, hormone replacement therapy, and periodontal attachment loss in Southern Brazilian women. / Haas, Alex N.; Rosing, Cassiano K.; Oppermann, Rui V.; Albandar, Jasim M.; Susin, Cristiano.

In: Journal of periodontology, Vol. 80, No. 9, 01.09.2009, p. 1380-1387.

Research output: Contribution to journalArticle

Haas, Alex N. ; Rosing, Cassiano K. ; Oppermann, Rui V. ; Albandar, Jasim M. ; Susin, Cristiano. / Association among menopause, hormone replacement therapy, and periodontal attachment loss in Southern Brazilian women. In: Journal of periodontology. 2009 ; Vol. 80, No. 9. pp. 1380-1387.
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abstract = "Background: The aim of the present study was to evaluate the association among menopause, hormone replacement therapy (HRT), and periodontal attachment loss (PAL). Methods: Three hundred twenty-eight women (40 to 69 years old) who participated in a previous oral survey in South Brazil were included. Women who reported not having their monthly menstrual cycles for ≥12 months were classified as postmenopausal. Postmenopausal women were categorized according to HRT. Women with ≥30{\%} teeth with PAL ≥5mm were classified as having periodontitis. The data were analyzed using a multivariable logistic regression model and adjusted for age, smoking, socioeconomic status, and dental care. Results: The prevalence of periodontitis was significantly greater among postmenopausal women not using HRT (HRT-) than among premenopausal women (64.4{\%} versus 46.3{\%}; P = 0.005). Similarly, the multivariable analysis demonstrated a significantly higher chance of having periodontitis in postmenopausal HRT- women than in premenopausal women (odds ratio [OR], 2.1; 95{\%} confidence interval [CI]: 1.1 to 4.0). In contrast, no significant differences were observed in the prevalence of periodontitis between postmenopausal women using HRT (HRT+) and premenopausal women (48.8{\%} versus 46.3{\%}; P = 0.77). After adjusting for cofactors, postmenopausal HRT+ women did not have a greater likelihood of having peri- odontitis than premenopausal women (OR, 1.2; 95{\%} CI: 0.6 to 2.5). No significant differences in tooth loss were observed among the study groups after adjusting for confounders. Conclusions: Postmenopausal HRT- women had a greater chance of having periodontitis than premenopausal women. In contrast, postmenopausal HRT+ women and premeno- pausal women had similar periodontal status. HRT may have a beneficial effect on periodontal health.",
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KW - Risk factors

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