Atorvastatin prevents endothelial dysfunction in high glucose condition through Skp2-mediated degradation of FOXO1 and ICAM-1

Medicine & Life Sciences

• S-Phase Kinase-Associated Proteins 100%
• Atorvastatin 73%
• Intercellular Adhesion Molecule-1 63%
• Glucose 38%
• Ubiquitination 24%
• Forkhead Box Protein O1 9%
• Monocytes 9%
• Endothelial Cells 8%
• 3-hydroxy-3-methylglutaryl-coenzyme A 7%
• Protease Inhibitors 5%
• Protein Binding 5%
• Hydroxymethylglutaryl-CoA Reductase Inhibitors 5%
• Immunoprecipitation 5%
• Oxidoreductases 5%
• In Vitro Techniques 2%

Chemical Compounds

• Atorvastatin 90%
• Glucose 44%
• Protein 25%
• Hyperglycemic 8%
• Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor 8%
• Coenzyme A 6%
• Protease Inhibitor 6%
• Protective 4%
• Molecule 3%