Attentional mechanisms during the intracarotid amobarbital test

K. Huh, K. J. Meador, D. W. Loring, G. P. Lee, B. S. Brooks

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

We investigated the integrity of attentional mechanisms following unilateral intracarotid amobarbital injection in 23 patients undergoing preoperative evaluation for epilepsy surgery. Performance for ipsilateral hand-button response to a quasi-random strobe flash was markedly altered following unilateral amobarbital injection as evidenced by decreased correct responses and increased perseverative errors. The increase in perseverations was inversely correlated with subsequent memory performance. The results indicate that unilateral amobarbital injection commonly produces a marked reduction in attention as well as disturbances in strategic control mechanisms.

Original languageEnglish (US)
Pages (from-to)1183-1186
Number of pages4
JournalNeurology
Volume39
Issue number9
DOIs
StatePublished - Sep 1989

ASJC Scopus subject areas

  • Clinical Neurology

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