Atypical presentation of chronic granulomatous disease with Burkholderia cepacia

Justin M Vining, Nirupma Sharma, Margaret Frank Guill

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Chronic granulomatous disease (CGD) is a rare inherited disorder of neutrophil oxidative burst. In patients with CGD, phagocyte destruction of catalase-producing organisms is impaired, resulting in recurrent and potentially fatal infections. Burkholderia cepacia, a catalase-producing organism, is known to infect patients with dysfunctional immune systems. We report a case of a 3-year-old boy with this rare infection that unravelled the diagnosis of CGD.

Original languageEnglish (US)
Article numberA1607
JournalBMJ Case Reports
DOIs
StatePublished - Aug 6 2014

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Burkholderia cepacia
Chronic Granulomatous Disease
Catalase
Respiratory Burst
Phagocytes
Infection
Immune System
Neutrophils

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Atypical presentation of chronic granulomatous disease with Burkholderia cepacia. / Vining, Justin M; Sharma, Nirupma; Guill, Margaret Frank.

In: BMJ Case Reports, 06.08.2014.

Research output: Contribution to journalArticle

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